Interactive Protein Comparison Table

pair_id#RESMSA: DEPTH; #RES; #ClustersPAIR_TMΔG1ΔG2AF2Clust_TM1AF2Clust_TM2AF2Deep_TM1AF2Deep_TM2AF3Clust_TM1AF3Clust_TM2AF3Deep_TM1AF3Deep_TM2ESM2_TM1ESM2_TM2ESM3_TM1ESM3_TM2MSATrans_CMAP_PR1MSATrans_CMAP_PR2MSATrans_CMAP_RE1MSATrans_CMAP_RE2
1dzlA_5keqF4732112; 473; 50.9304648.70015504.3700.920(2)0.880(2)0.9200.9200.930(2)0.890(2)0.9300.9200.4000.3900.4000.3700.6600.6400.1500.160
1eboE_5fhcJ1111325; 131; 20.2454828.2301508.5500.790(0)0.590(0)0.7800.5900.750(0)0.340(0)0.7500.2700.7900.3500.7900.3500.0000.0000.0000.000
1fzpD_2frhA1272833; 127; 80.6395748.3301127.2100.630(2)0.900(2)0.6300.9100.650(2)0.940(2)0.6500.9400.6200.8500.6200.8500.0200.4100.0600.420
1iytA_2naoF42150; 42; 10.2305654692.29036522235.9900.240(0)0.220(0)0.2400.2200.480(0)0.240(0)0.4800.2400.4300.2900.4300.240--0.0000.000
1jfkA_2nxqB13416550; 134; 210.433744.000189.8100.460(12)0.540(19)0.4600.4600.450(6)0.710(8)0.4500.4600.5200.9000.5200.9000.3900.2500.4600.740
1kctA_3t1pA37519991; 375; 200.8146033.4901525.9600.940(8)0.830(0)0.9400.8300.940(8)0.840(9)0.9400.8400.9400.8500.9400.8500.7400.7200.2800.320
1miqB_1qs8B37518863; 375; 150.8701399.9006604.6800.950(0)0.960(0)0.9400.9600.930(0)0.970(0)0.9100.9700.9000.9700.9000.9700.6600.6600.2800.300
1mnmD_1mnmC776577; 77; 200.753431.950431.9500.720(15)0.750(1)0.7200.7500.720(1)0.730(1)0.7100.7200.7300.7600.7300.7600.3600.3800.4600.470
1nocA_1qomB4209546; 420; 190.8791300.2001418.0000.870(2)0.890(2)0.8800.9300.880(2)0.930(2)0.8800.9300.4200.3900.4100.4000.4700.5700.2000.210
1nqjB_1nqdA1144069; 115; 150.884-289.470367.1300.980(2)0.980(2)0.9800.9800.980(2)0.980(2)0.9800.9800.9700.9700.9700.9700.6800.4100.2000.220
1nrjB_2gedB1915939; 223; 180.608-211.26099.7300.350(5)0.630(16)0.3500.6100.350(5)0.630(16)0.3500.6200.3700.8000.3700.8000.0700.0600.0100.020
1qb3A_3qy2A1136217; 118; 200.783963.850204.1000.730(3)0.920(3)0.7300.9200.740(3)0.910(3)0.7400.9200.7000.8700.7000.8700.1400.0800.0300.020
1qlnA_1h38D86210300; 882; 110.7305492.52020547.2400.850(2)0.950(0)0.8300.9500.900(8)0.950(2)0.9000.9500.8300.8700.8300.8700.0400.0400.0200.020
1rk4B_1k0nA2266001; 229; 160.804-294.970-2.0000.800(5)0.910(1)0.8000.9600.810(5)0.980(1)0.8000.9800.8000.9400.8000.9400.1900.3300.1400.220
1svfC_4wsgC479820; 479; 10.831-174.3307362.6600.940(0)0.700(0)0.9200.6400.800(0)0.520(0)0.7900.4600.7100.5800.7100.5800.0000.480-0.140
1wp8C_5ejbC454508; 454; 10.492371.88021399.8000.700(0)0.680(0)0.6900.6800.640(0)0.600(0)0.6400.6000.6400.6200.6400.6200.5600.5200.3200.130
1x0gD_1x0gA10414425; 106; 210.5532021.2202021.2200.900(3)0.900(3)0.9100.9100.910(3)0.910(3)0.9100.9100.9200.9200.9200.9200.3100.6700.5800.450
1xezA_3o44A6631128; 663; 10.601-500.170-2226.5700.630(0)0.870(0)0.6400.6800.620(0)0.870(0)0.6200.8800.5500.670--0.6900.7100.1200.120
1xjuB_1xjtA1705318; 178; 180.762-400.890216.4500.790(16)0.970(16)0.7800.9800.830(16)0.980(16)0.8100.9700.7900.9300.7900.9300.4700.2200.4400.040
1xtgB_3j97M13110401; 131; 200.344172.60041553.1400.070(7)0.090(1)0.0700.1000.080(13)0.090(1)0.0800.1000.1500.1000.1500.1000.0000.4100.0000.740
1zk9A_3jv6A1105780; 110; 200.534165.4201178.6100.520(15)0.980(15)0.4900.9800.530(11)0.990(19)0.4900.9800.5300.9800.5300.9800.5800.7000.4400.390
2bzyB_2lqwA30221426; 303; 40.599255.480164131771.5600.690(0)0.340(0)0.7000.3900.710(0)0.380(0)0.7300.3800.6900.3800.6900.3800.2800.6100.4800.250
2c1vB_2c1uC33532272; 335; 180.872-1155.090195.3700.990(0)0.870(9)0.9800.8700.990(0)0.870(9)0.9900.8700.9600.8600.9600.8600.5500.4300.2200.200
2grmB_2axzA3157574; 315; 00.9501607.4002909.280--0.9000.890--0.9200.9200.9000.9000.9000.900----
2h44A_1rkpA32618182; 326; 200.927-369.680-30.0800.940(1)0.960(1)0.9400.9600.940(1)0.960(1)0.9400.9600.9400.9600.9400.9600.4600.4700.4200.440
2jmrA_4j3oF1796956; 179; 200.803141981127.9001260.0900.850(4)0.820(5)0.8500.8100.850(4)0.830(5)0.8500.8300.8400.8500.8400.8500.6600.5800.3200.400
2k42A_1ceeB726099; 81; 200.28586490930.230124681562.5600.820(3)0.220(15)0.7900.2200.830(10)0.210(3)0.8200.2100.7900.2300.7900.2301.0000.6700.0700.110
2kb8A_6vw2A37562; 37; 20.24241783100.730962.7300.510(1)0.180(0)0.5400.2000.570(1)0.160(0)0.6000.1500.5400.1800.5400.1901.0000.0000.0100.000
2kkwA_2n0aD140984; 140; 30.189109648624.3702471.7800.350(1)0.250(1)0.3600.1800.330(1)0.220(2)0.3100.1800.3100.2600.3100.2700.0000.0000.0000.000
2lelA_2k0qA74513; 74; 10.54260669238.58063126810.6500.600(0)0.730(0)0.6000.7300.700(0)0.630(0)0.7000.6300.5900.7600.5900.7600.7700.8400.3000.310
2lepA_4hddA645645; 67; 200.39666444166.78013.1100.760(9)0.520(9)0.7600.5200.760(9)0.520(9)0.7600.5100.8000.5100.8000.5100.8300.0700.4700.270
2lv1A_6lniA147845; 147; 30.251115517181.1901761.3600.610(1)0.330(1)0.5900.2700.600(1)0.280(1)0.6000.2800.5900.3200.5900.3200.5000.1300.0700.500
2mwfA_2nntA3227450; 38; 210.20331463121.98030501989.1300.610(3)0.240(16)0.5900.2000.560(6)0.250(16)0.5400.2100.6000.2600.6000.2600.1200.0000.0300.000
2n54B_2hdmA748000; 75; 210.33888033507.85058903203.9400.400(15)0.720(5)0.3800.7700.430(12)0.730(5)0.3800.7800.4100.7500.4100.7500.5700.9000.2100.450
2namA_1uxmK15321236; 153; 210.185714316.1401087.2800.190(14)0.990(8)0.1700.9900.190(16)0.990(1)0.1800.9900.2200.9900.2300.9900.0400.8000.1300.380
2p3vD_2p3vA2548979; 254; 190.956591.370591.3700.970(0)0.970(0)0.9800.9800.970(6)0.970(6)0.9400.9400.9400.9400.9400.9400.5800.6000.4300.430
2pbkB_3njqA227364; 228; 10.8491023.510603.9200.980(0)0.860(0)0.9800.8600.980(0)0.860(0)0.9800.8700.8500.9100.8400.9100.3400.3000.0400.030
2qqjA_4qdsA31517346; 319; 180.887-295.060-250.0300.980(13)0.890(0)0.9900.8900.990(13)0.970(3)0.9800.8800.9700.8900.9700.8900.2600.4200.1200.240
2uy7D_5fluE1635681; 163; 210.7262914.580-1506.6500.340(14)0.930(6)0.3400.9300.340(14)0.900(6)0.3400.9200.3500.8300.3500.8300.5000.5300.3000.310
2vfxL_3gmhL2036124; 203; 200.70017194.7909928.3700.940(9)0.970(9)0.9400.9700.940(9)0.970(9)0.9200.9300.9400.9500.9400.9500.4000.6700.0900.280
2wcdX_4phqA291287; 291; 10.50918041.940-1279.2200.540(0)0.890(0)0.5400.8900.520(0)0.930(0)0.5200.9400.5900.8200.5900.8200.4100.0200.2200.010
2z9oB_1repC2184821; 227; 160.5944726.5601503.4700.620(2)0.830(2)0.6300.8900.660(2)0.920(2)0.6200.9800.6800.9300.6800.9300.0600.0600.0400.040
3g0hA_3ewsB40831306; 418; 180.626400.6201387.8400.910(0)0.890(0)0.9100.8900.900(12)0.720(12)0.9000.7200.9200.7300.9200.7300.0800.0800.0300.030
3hdfA_3hdeA16517609; 165; 210.774-180.93094.3300.830(11)0.980(1)0.8000.9800.800(1)0.980(1)0.8000.9800.7700.8800.7700.8800.2400.4500.3800.450
3j7vG_3j7wB3432109; 343; 50.69647796.59024007.5900.860(4)0.700(4)0.8600.7900.860(4)0.720(4)0.8600.7900.8400.7500.8400.7500.3400.3500.2000.200
3kdsG_2ce7C42661434; 435; 190.5471702.7806812.9500.870(14)0.750(16)0.8100.7500.850(14)0.800(0)0.8200.8100.8800.7100.8800.7100.6300.1200.4000.070
3l5nB_2a73B97611084; 982; 140.30213397.8708852.6400.280(0)0.290(0)0.2800.2900.290(4)0.280(5)0.2800.2700.2900.3100.2800.2800.3600.3500.1000.100
3l9qB_4rr2D4298808; 430; 140.872-147.1506222.2000.860(13)0.280(9)0.8600.2900.860(9)0.280(9)0.8600.2800.8600.2900.8600.2900.1200.5400.0900.350
3lowA_3m1bF1007853; 100; 200.547295.76022896.3000.570(13)0.320(15)0.5600.3200.570(13)0.320(13)0.5700.3200.5700.3400.5700.3400.3301.0000.3300.350
3lqcA_1xntA1514032; 152; 110.722-12.260196708343.5000.760(12)0.870(12)0.7800.8800.770(0)0.860(12)0.7800.8900.7700.8800.7700.8800.5000.3500.2200.130
3m7pA_3ejhA30110678; 310; 70.50012282.8201813.3800.380(1)0.760(1)0.3800.9300.380(6)0.630(2)0.3800.7900.4000.8800.4000.8800.5500.2100.1000.050
3meeA_4b3oB5528751; 552; 100.4541816.5002404.0100.800(1)0.780(1)0.6200.6400.820(2)0.800(2)0.8200.8000.7900.8000.7900.8000.6100.5000.2100.180
3mkoA_5ineA348469; 348; 10.321274.42032695.9000.480(0)0.610(0)0.5000.5100.500(0)0.450(0)0.4900.4500.5400.3000.5400.3100.0000.8000.0000.030
3r9jC_2kxoA8914714; 90; 200.420757.00035755611.3100.190(2)0.740(2)0.1500.3900.170(2)0.680(2)0.1600.5700.1800.5800.1900.5800.5000.4800.3600.500
3t5oA_4a5wB87136901; 901; 20.58712126.57013780.2000.610(1)0.150(0)0.6000.1500.600(0)0.180(1)0.6000.1600.5400.1900.5400.1900.3000.3300.0400.050
3v0tA_3uyiA31238736; 313; 200.925203.78041.2700.940(5)0.880(5)0.9500.8800.940(5)0.880(5)0.9400.8800.9500.8700.9500.8700.5400.4000.3800.260
3ztjE_5hmgA3281832; 328; 50.99431555.32019680.5400.820(0)0.800(0)0.9300.9000.840(0)0.820(0)0.9500.9400.5700.5600.5700.5500.3500.3700.0300.030
3zxgB_5ec5P293113; 293; 00.580329.4008919.940--0.8800.540--0.9100.5600.7800.5700.7800.5700.6900.6900.1400.150
4aalA_4aanA32331699; 324; 190.880-158.410-491.2700.880(0)0.990(0)0.8800.9900.880(0)1.000(0)0.8800.9900.8600.9700.8600.9700.1700.0600.0700.020
4cmqB_4zt0C12768978; 1338; 70.5444266.4504201.9800.550(0)0.760(0)0.5500.7600.530(0)0.830(0)0.5300.8300.4200.6400.3000.2600.0700.0500.0400.040
4dxrA_4dxtA1987449; 198; 200.9291125.280135.7700.930(15)0.890(3)0.9200.9100.930(15)0.890(3)0.9400.9200.9100.8700.9100.8700.3900.0300.1500.020
4g0dZ_4fu4C2610; 26; 00.3261245.3101806.020--0.0600.060--0.0600.0600.0500.0600.0500.060----
4gqcB_4gqcC16117788; 161; 210.920-990.730-990.7300.920(3)0.920(3)0.9200.9200.920(3)0.920(3)0.9200.9200.9200.9200.9200.9200.1700.2600.1200.170
4h2aA_3j9cA7045321; 724; 30.737-1090.610544.3400.850(0)0.770(1)0.8600.7600.920(0)0.850(0)0.8100.7800.7400.7200.7400.7300.2800.1000.0900.050
4n9wA_4nc9C36017642; 370; 170.829-605.3003194.4800.910(0)0.860(1)0.9000.8600.910(0)0.840(1)0.9100.8400.9100.8300.9100.8300.1300.1400.0700.090
4o01D_4o0pA48516495; 491; 160.848447.620896.8900.630(1)0.730(0)0.6200.7300.840(5)0.950(1)0.8200.9300.9500.8900.9500.8900.4200.3900.2500.230
4ow6B_4ae0A499142; 523; 00.6502467.500-231.350--0.4700.400--0.5100.4200.4500.4800.4500.4700.0500.0500.0000.000
4pyjA_4pyiA20815552; 208; 190.882-217.200-317.5900.890(0)0.950(0)0.8900.9500.890(0)0.960(17)0.8900.9500.8800.9600.8800.9600.5800.1100.4600.070
4q79F_4uv2D2306240; 240; 190.7649311.180-1527.3300.850(7)0.850(11)0.9000.8400.930(4)0.920(11)0.8000.9400.8300.8500.8300.8500.5100.4000.3200.090
4qhhA_4qhfA1092560; 109; 100.645130.98059.7500.650(0)0.950(0)0.6400.9500.640(0)0.950(0)0.6400.9500.6500.9400.6500.9400.3900.5800.3200.470
4rmbB_4rmbA15551; 155; 00.955-30.110-30.110--0.8400.840--0.8500.8500.7700.7700.7700.7700.4100.4100.0500.050
4rwqB_4rwnA3493917; 349; 110.8941486.060-202.3300.940(1)0.930(8)0.9400.9400.950(6)0.940(2)0.9400.9300.9000.9700.9000.9700.4900.4200.1600.110
4tsyD_3zwgN1781090; 178; 10.851-400.740279.9600.850(0)0.990(0)0.8500.9900.850(0)0.990(0)0.8500.9900.8500.9800.8500.9800.6800.6600.3100.260
4xwsD_4y0mJ20617709; 209; 200.932992.600-253.8000.860(7)0.960(7)0.8700.9700.870(7)0.950(7)0.8700.9600.8700.9200.8700.9200.6600.2100.4500.170
4ydqB_4twaA48829788; 488; 170.941-193.3902114.8700.990(3)0.930(3)0.9800.9200.990(3)0.930(3)0.9900.9300.9700.9200.9700.9200.0400.1000.0200.050
4yhdG_7ahlE293588; 293; 20.826524.0501564.0700.960(0)0.780(0)0.9600.7900.980(0)0.790(0)0.9800.7900.8600.7100.8600.7100.6100.5500.1900.230
4zrbH_4zrbC1265377; 126; 210.929-1396.520-1396.5200.980(13)0.980(13)0.9900.9900.990(13)0.990(13)0.9900.9900.9300.9300.9300.9300.8300.8100.4900.450
5bmyA_5b3zA4028635; 403; 160.941434.2802068.2600.940(0)0.890(5)0.9400.8900.940(7)0.890(7)0.9400.8900.9400.8900.9400.8900.2100.2300.1300.150
5c1vB_5c1vA31732596; 318; 180.9413268.9503268.9500.990(10)0.990(10)0.9900.9900.990(10)0.990(10)0.9900.9900.9900.9900.9900.9900.5200.5200.2400.220
5c3iF_3kuyA9616151; 97; 00.795------------------
5et5A_3ifaA32629615; 326; 200.969-176.370-742.9700.970(3)0.950(3)0.9700.9600.970(3)0.960(3)0.9800.9600.9600.9300.9600.9300.6200.1000.3100.050
5f5rB_5f3kA22232225; 225; 190.779-109.340-181.0300.930(12)0.800(3)0.9300.8000.900(12)0.790(12)0.9200.8000.8600.7900.8600.7900.1100.0900.0400.040
5hk5H_4jphB1193332; 119; 120.7272084.100982.1400.640(10)0.710(10)0.7000.7400.680(3)0.740(3)0.6400.7400.6800.7000.6800.7000.8300.8600.3300.320
5i2sA_5i2mA413154; 413; 10.3732904.0201353.9000.420(0)0.570(0)0.4200.5500.530(0)0.480(0)0.5300.4200.4900.5100.4900.5000.6200.6200.0300.040
5jytA_2qkeE10614458; 108; 220.453105752958.5902865.5000.830(5)0.520(5)0.7500.4900.840(12)0.530(19)0.7500.4700.7800.4900.7800.4900.6100.3200.3800.210
5jztG_5jzhA424725; 424; 10.57362318.250-6165.0400.600(0)0.920(0)0.6000.8800.600(0)0.930(0)0.6000.9400.5200.6900.5200.6900.5200.5500.2800.240
5l35G_5l35D422256; 422; 10.8951785.0001785.0000.860(0)0.860(0)0.8400.8400.860(0)0.860(0)0.8600.8600.8400.8400.8400.8400.4600.4800.2400.240
5lj3M_3tp2A2529773; 252; 60.81889711.770-6.7500.900(0)0.890(4)0.9200.9100.900(5)0.910(4)0.9000.8600.8500.8900.8500.8900.6700.7600.1600.190
5ly6B_5aoeB4882201; 488; 40.47811056.9902118.0300.480(1)0.810(0)0.4800.8000.480(0)0.890(1)0.4800.8900.4700.8400.4700.8400.5300.5500.2900.280
5tpnA_1g2cF490308; 490; 00.7183135.8701208.100--0.3500.820--0.6600.8200.5800.8400.5800.8400.1900.0000.020-
5wrgC_1wyyB7361282; 736; 20.41925448.540112.2900.470(1)0.620(0)0.4800.6200.370(1)0.630(1)0.3400.7000.3000.6300.3000.6400.6700.0000.0400.000
6c6sD_2ougC16111386; 161; 190.5924248.9404501.1300.600(16)0.890(14)0.5600.8900.790(14)0.900(14)0.5600.9000.5800.8300.5800.8300.6300.4700.4700.380
7kdtB_6z4uA8423; 84; 00.232-817.6702921.690--0.4300.260--0.4000.2800.3700.2300.3700.2300.0001.0000.0000.010
Averages292.43 (219.56)10302 ; 296.05 ; 11.760.66 (0.23)9288856.09 (28682760.66)7724433.02 (30864262.91)0.73 (0.23)0.75 (0.24)0.71 (0.24)0.73 (0.26)0.74 (0.22)0.75 (0.25)0.72 (0.23)0.74 (0.27)0.69 (0.23)0.71 (0.25)0.69 (0.23)0.71 (0.26)0.41 (0.25)0.40 (0.27)0.20 (0.16)0.20 (0.17)

#RES: Number of residues in the longer chain of the pair.

MSA: DEPTH; #RES; #Clusters: DEPTH = number of sequences in DeepMsa.a3m; #RES = alignment width (columns, including gaps); #Clusters = count of ShallowMsa_* a3m files.

PAIR_TM: TM-score between the two ground-truth folds (max of the two directions).

ΔG1: Rosetta full-atom (Ref2015) energy of Fold1 (lower is more stable).

ΔG2: Rosetta full-atom (Ref2015) energy of Fold2 (lower is more stable).

AF2Clust_TM1: Best TM-score to Fold1 among AF2 predictions built from any shallow cluster (number in parentheses is the cluster id).

AF2Clust_TM2: Best TM-score to Fold2 among AF2 predictions from shallow clusters.

AF2Deep_TM1: Best TM-score to Fold1 among AF2 predictions built from the DeepMsa alignment.

AF2Deep_TM2: Best TM-score to Fold2 among AF2 predictions from DeepMsa.

AF3Clust_TM1: Best TM-score to Fold1 among AF3 predictions from shallow clusters.

AF3Clust_TM2: Best TM-score to Fold2 among AF3 predictions from shallow clusters.

AF3Deep_TM1: Best TM-score to Fold1 among AF3 predictions from DeepMsa.

AF3Deep_TM2: Best TM-score to Fold2 among AF3 predictions from DeepMsa.

ESM2_TM1: Best TM-score to Fold1 among all ESMFold(ESM2) predictions (across all sampled sequences from all clusters; no MSA used).

ESM2_TM2: Best TM-score to Fold2 among all ESMFold(ESM2) predictions.

ESM3_TM1: Best TM-score to Fold1 among all ESMFold(ESM3) predictions.

ESM3_TM2: Best TM-score to Fold2 among all ESMFold(ESM3) predictions.

MSATrans_CMAP_PR1: Maximum precision of MSA-Transformer contact map vs Fold1 truth (threshold=0.4; |i−j|≥6).

MSATrans_CMAP_PR2: Maximum precision vs Fold2 truth (same settings).

MSATrans_CMAP_RE1: Maximum recall vs Fold1 truth.

MSATrans_CMAP_RE2: Maximum recall vs Fold2 truth.

Note: rows shown dimmed have fewer than 2 clusters in the shallow MSA and are de-emphasized.