Analysis of 2p3vD

cluster	n	neff	AF2_TM1	AF2_TM2	AF3_TM1	AF3_TM2	RE-MSAT-COM	RE-MSAT1	RE-MSAT2	ESM_SEQIDS	ESM_TM1_LIST	ESM_TM2_LIST
Deep	-	-	0.98	0.98	0.94	0.94	0.48	0.48	0.5	-	-	-
000	-	-	0.97	0.97	0.94	0.94	0.47	0.47	0.49	001; 001; 004; 003; 008; 008; 004; 003; 002; 007	0.94; 0.94; 0.86; 0.86; 0.86; 0.86; 0.86; 0.86; 0.84; 0.84	0.94; 0.94; 0.86; 0.86; 0.86; 0.86; 0.86; 0.86; 0.84; 0.84
001	-	-	0.85	0.85	0.86	0.86	0.47	0.47	0.48	005; 005; 004; 004; 006; 006; 001; 002; 002; 001	0.90; 0.90; 0.87; 0.87; 0.87; 0.87; 0.86; 0.86; 0.86; 0.86	0.90; 0.90; 0.87; 0.87; 0.87; 0.87; 0.86; 0.86; 0.86; 0.86
002	-	-	0.85	0.85	0.85	0.85	0.09	0.09	0.09	001; 002; 004; 001; 004; 002; 005; 005; 006; 006	0.87; 0.87; 0.87; 0.87; 0.87; 0.87; 0.86; 0.86; 0.85; 0.85	0.87; 0.87; 0.87; 0.87; 0.87; 0.87; 0.86; 0.86; 0.85; 0.85
003	-	-	0.93	0.93	0.92	0.92	0.05	0.06	0.06	001; 001; 005; 005; 002; 002; 004; 003; 003; 004	0.89; 0.89; 0.88; 0.88; 0.87; 0.87; 0.86; 0.86; 0.86; 0.86	0.89; 0.89; 0.88; 0.88; 0.87; 0.87; 0.86; 0.86; 0.86; 0.86
004	-	-	0.85	0.85	0.85	0.85	0.45	0.44	0.46	001; 002; 002; 001; 007; 006; 006; 007; 005; 005	0.87; 0.87; 0.87; 0.87; 0.86; 0.86; 0.86; 0.86; 0.84; 0.84	0.87; 0.87; 0.87; 0.87; 0.86; 0.86; 0.86; 0.86; 0.84; 0.84
005	-	-	0.84	0.84	0.84	0.84	0.14	0.14	0.15	001; 001; 004; 004; 006; 006; 007; 009; 009; 007	0.91; 0.91; 0.90; 0.90; 0.89; 0.89; 0.88; 0.88; 0.88; 0.88	0.91; 0.91; 0.90; 0.90; 0.89; 0.89; 0.88; 0.88; 0.88; 0.88
006	-	-	0.97	0.97	0.97	0.97	0.49	0.5	0.5	001; 001; 006; 002; 002; 006; 007; 007; 003; 003	0.94; 0.94; 0.89; 0.89; 0.89; 0.89; 0.87; 0.87; 0.86; 0.86	0.94; 0.94; 0.89; 0.89; 0.89; 0.89; 0.87; 0.87; 0.86; 0.86
007	-	-	0.8	0.8	0.83	0.83	0.06	0.06	0.06	003; 003; 001; 001; 002; 002; 004; 004; 006; 006	0.88; 0.88; 0.87; 0.87; 0.86; 0.86; 0.85; 0.85; 0.82; 0.82	0.88; 0.88; 0.87; 0.87; 0.86; 0.86; 0.85; 0.85; 0.82; 0.82
008	-	-	0.86	0.86	0.85	0.85	0.08	0.08	0.08	003; 003; 002; 001; 002; 001; 005; 005; 007; 007	0.89; 0.89; 0.87; 0.87; 0.87; 0.87; 0.86; 0.86; 0.86; 0.86	0.89; 0.89; 0.87; 0.87; 0.87; 0.87; 0.86; 0.86; 0.86; 0.86
009	-	-	0.7	0.7	0.73	0.73	0.48	0.48	0.49	008; 008; 001; 001; 009; 009; 004; 004; 003; 003	0.88; 0.88; 0.87; 0.87; 0.87; 0.87; 0.85; 0.85; 0.82; 0.82	0.88; 0.88; 0.87; 0.87; 0.87; 0.87; 0.85; 0.85; 0.82; 0.82
010	-	-	0.81	0.81	0.81	0.81	0.13	0.13	0.14	001; 005; 001; 005; 004; 004; 006; 006; 007; 002	0.88; 0.88; 0.88; 0.88; 0.87; 0.87; 0.86; 0.86; 0.85; 0.85	0.88; 0.88; 0.88; 0.88; 0.87; 0.87; 0.86; 0.86; 0.85; 0.85
011	-	-	0.92	0.92	0.91	0.91	0.15	0.15	0.16	007; 007; 006; 006; 001; 001; 005; 005; 008; 008	0.90; 0.90; 0.89; 0.89; 0.88; 0.88; 0.87; 0.87; 0.86; 0.86	0.90; 0.90; 0.89; 0.89; 0.88; 0.88; 0.87; 0.87; 0.86; 0.86
012	-	-	0.88	0.88	0.89	0.89	0.44	0.44	0.45	001; 001; 004; 004; 005; 005; 003; 002; 002; 003	0.90; 0.90; 0.89; 0.89; 0.88; 0.88; 0.86; 0.86; 0.86; 0.86	0.90; 0.90; 0.89; 0.89; 0.88; 0.88; 0.86; 0.86; 0.86; 0.86
013	-	-	0.92	0.92	0.94	0.94	0.06	0.07	0.08	009; 009; 008; 008; 001; 006; 006; 001; 002; 002	0.91; 0.91; 0.90; 0.90; 0.89; 0.89; 0.89; 0.89; 0.88; 0.88	0.91; 0.91; 0.90; 0.90; 0.89; 0.89; 0.89; 0.89; 0.88; 0.88
014	-	-	0.79	0.79	0.78	0.78	0.11	0.11	0.1	001; 008; 001; 006; 008; 006; 002; 002; 007; 007	0.90; 0.90; 0.90; 0.89; 0.89; 0.89; 0.88; 0.88; 0.87; 0.87	0.90; 0.90; 0.90; 0.89; 0.89; 0.89; 0.88; 0.88; 0.87; 0.87
015	-	-	0.79	0.79	0.79	0.79	0.12	0.12	0.14	004; 004; 009; 009; 003; 003; 002; 002; 006; 005	0.90; 0.90; 0.84; 0.84; 0.83; 0.83; 0.83; 0.83; 0.80; 0.80	0.90; 0.90; 0.84; 0.84; 0.83; 0.83; 0.83; 0.83; 0.80; 0.80
016	-	-	0.92	0.92	0.92	0.92	0.1	0.11	0.1	001; 001; 006; 006; 007; 008; 007; 008; 002; 002	0.90; 0.90; 0.89; 0.89; 0.87; 0.87; 0.87; 0.87; 0.86; 0.86	0.90; 0.90; 0.89; 0.89; 0.87; 0.87; 0.87; 0.87; 0.86; 0.86
017	-	-	0.88	0.88	0.87	0.87	0.09	0.09	0.08	005; 005; 006; 006; 001; 004; 004; 001; 002; 002	0.92; 0.92; 0.90; 0.90; 0.88; 0.88; 0.88; 0.88; 0.87; 0.87	0.92; 0.92; 0.90; 0.90; 0.88; 0.88; 0.88; 0.88; 0.87; 0.87
018	-	-	0.79	0.79	0.79	0.79	0.48	0.48	0.48	004; 004; 001; 001; 002; 002; 003; 005; 003; 005	0.90; 0.90; 0.87; 0.87; 0.86; 0.86; 0.85; 0.85; 0.85; 0.85	0.90; 0.90; 0.87; 0.87; 0.86; 0.86; 0.85; 0.85; 0.85; 0.85

Aligned per-residue ΔΔG

aln_pos	aa1	aa2	E1	E2
1	M	M	5.47	5.47
2	D	D	2.04	2.04
3	R	R	0.01	0.01
4	L	L	-1.89	-1.89
5	D	D	-2.73	-2.73
6	F	F	-2.65	-2.65
7	S	S	-0.85	-0.85
8	I	I	-2.0	-2.0
9	K	K	-0.05	-0.05
10	L	L	-3.87	-3.87
11	L	L	-0.04	-0.04
12	R	R	-3.3	-3.3
13	K	K	-1.96	-1.96
14	V	V	-2.0	-2.0
15	G	G	-0.81	-0.81
16	H	H	-1.34	-1.34
17	L	L	3.28	3.28
18	L	L	-3.96	-3.96
19	M	M	-2.42	-2.42
20	I	I	-0.19	-0.19
21	H	H	-2.58	-2.58
22	W	W	-1.23	-1.23
23	G	G	-1.09	-1.09
24	R	R	7.3	7.3
25	V	V	0.02	0.02
26	D	D	5.39	5.39
27	N	N	4.82	4.82
28	V	V	-0.83	-0.83
29	E	E	1.54	1.54
30	K	K	47.93	47.93
31	K	K	16.49	16.49
32	T	T	10.18	10.18
33	G	G	4.92	4.92
34	F	F	9.52	9.52
35	K	K	14.51	14.51
36	D	D	3.75	3.75
37	I	I	-1.34	-1.34
38	V	V	1.34	1.34
39	T	T	-1.26	-1.26
40	E	E	3.53	3.53
41	I	I	1.91	1.91
42	D	D	2.36	2.36
43	R	R	5.08	5.08
44	E	E	5.88	5.88
45	A	A	-3.07	-3.07
46	Q	Q	2.12	2.12
47	R	R	6.45	6.45
48	M	M	2.5	2.5
49	I	I	-5.13	-5.13
50	V	V	-2.64	-2.64
51	D	D	0.42	0.42
52	E	E	-2.05	-2.05
53	I	I	-4.05	-4.05
54	R	R	-1.15	-1.15
55	K	K	-0.3	-0.3
56	F	F	0.46	0.46
57	F	F	2.56	2.56
58	P	P	6.94	6.94
59	D	D	0.27	0.27
60	E	E	-0.57	-0.57
61	N	N	2.95	2.95
62	I	I	1.11	1.11
63	M	M	0.22	0.22
64	A	A	2.36	2.36
65	E	E	7.06	7.06
66	E	E	10.23	10.23
67	G	G	3.15	3.15
68	I	I	4.03	4.03
69	F	F	2.94	2.94
70	E	E	6.29	6.29
71	K	K	1.23	1.23
72	G	G	0.76	0.76
73	D	D	2.06	2.06
74	R	R	3.24	3.24
75	L	L	-3.39	-3.39
76	W	W	-5.22	-5.22
77	I	I	-2.71	-2.71
78	I	I	-1.85	-1.85
79	D	D	7.39	7.39
80	P	P	2.4	2.4
81	I	I	-0.55	-0.55
82	D	D	-1.59	-1.59
83	G	G	-1.07	-1.07
84	T	T	3.51	3.51
85	I	I	-0.58	-0.58
86	N	N	-2.82	-2.82
87	F	F	-6.18	-6.18
88	V	V	-2.45	-2.45
89	H	H	2.17	2.17
90	G	G	-3.46	-3.46
91	L	L	-1.89	-1.89
92	P	P	-3.64	-3.64
93	N	N	5.9	5.9
94	F	F	-4.96	-4.96
95	S	S	-3.31	-3.31
96	I	I	-4.91	-4.91
97	S	S	-1.68	-1.68
98	L	L	-2.78	-2.78
99	A	A	-2.85	-2.85
100	Y	Y	-2.93	-2.93
101	V	V	-3.4	-3.4
102	E	E	-1.42	-1.42
103	N	N	6.44	6.44
104	G	G	-1.98	-1.98
105	E	E	0.59	0.59
106	V	V	-2.63	-2.63
107	K	K	3.39	3.39
108	L	L	1.6	1.6
109	G	G	-0.56	-0.56
110	V	V	-3.54	-3.54
111	V	V	-4.53	-4.53
112	H	H	-1.14	-1.14
113	A	A	1.65	1.65
114	P	P	0.87	0.87
115	A	A	-1.94	-1.94
116	L	L	-0.94	-0.94
117	N	N	-0.87	-0.87
118	E	E	-0.88	-0.88
119	T	T	-1.63	-1.63
120	L	L	-1.73	-1.73
121	Y	Y	-4.63	-4.63
122	A	A	-3.48	-3.48
123	E	E	2.09	2.09
124	E	E	13.81	13.81
125	G	G	-1.28	-1.28
126	S	S	0.32	0.32
127	G	G	-2.17	-2.17
128	A	A	-2.24	-2.24
129	F	F	-1.85	-1.85
130	F	F	1.41	1.41
131	N	N	-4.43	-4.43
132	G	G	-1.41	-1.41
133	E	E	-0.51	-0.51
134	R	R	0.11	0.11
135	I	I	-1.38	-1.38
136	R	R	2.37	2.37
137	V	V	-0.51	-0.51
138	S	S	1.64	1.64
139	E	E	0.53	0.53
140	N	N	-0.08	-0.08
141	A	A	0.38	0.38
142	S	S	2.47	2.47
143	L	L	-2.79	-2.79
144	E	E	1.89	1.89
145	E	E	6.09	6.09
146	C	C	1.92	1.92
147	V	V	-1.42	-1.42
148	G	G	-2.05	-2.05
149	S	S	-2.45	-2.45
150	T	T	-1.71	-1.71
151	G	G	0.29	0.29
152	S	S	1.72	1.72
153	Y	Y	5.6	5.6
154	V	V	2.43	2.43
155	D	D	1.2	1.2
156	F	F	-1.77	-1.77
157	T	T	-2.08	-2.08
158	G	G	0.39	0.39
159	K	K	5.26	5.26
160	F	F	-3.15	-3.15
161	I	I	2.42	2.42
162	E	E	2.78	2.78
163	R	R	6.61	6.61
164	M	M	0.43	0.43
165	E	E	4.47	4.47
166	K	K	4.66	4.66
167	R	R	9.66	9.66
168	T	T	-1.44	-1.44
169	R	R	1.38	1.38
170	R	R	4.08	4.08
171	I	I	-0.66	-0.66
172	R	R	1.26	1.26
173	I	I	2.44	2.44
174	L	L	2.9	2.9
175	G	G	-0.51	-0.51
176	S	S	-0.78	-0.78
177	A	A	0.53	0.53
178	A	A	-2.85	-2.85
179	L	L	-3.47	-3.47
180	N	N	3.66	3.66
181	A	A	-3.34	-3.34
182	A	A	-4.5	-4.5
183	Y	Y	-1.06	-1.06
184	V	V	-2.95	-2.95
185	G	G	-0.45	-0.45
186	A	A	-0.96	-0.96
187	G	G	-1.43	-1.43
188	R	R	-1.49	-1.49
189	V	V	-0.39	-0.39
190	D	D	1.34	1.34
191	F	F	-2.84	-2.84
192	F	F	-4.61	-4.61
193	V	V	-5.41	-5.41
194	T	T	2.1	2.1
195	W	W	4.77	4.77
196	R	R	2.77	2.77
197	I	I	12.45	12.45
198	N	N	11.42	11.42
199	P	P	1.03	1.03
200	W	W	-0.05	-0.05
201	D	D	13.35	13.35
202	I	I	0.32	0.32
203	A	A	-2.11	-2.11
204	A	A	-2.05	-2.05
205	G	G	-0.54	-0.54
206	L	L	0.84	0.84
207	I	I	0.2	0.2
208	I	I	-5.23	-5.23
209	V	V	-4.05	-4.05
210	K	K	-1.35	-1.35
211	E	E	-2.71	-2.71
212	A	A	-3.34	-3.34
213	G	G	-2.28	-2.28
214	G	G	-1.6	-1.6
215	M	M	0.66	0.66
216	V	V	-3.73	-3.73
217	T	T	-3.11	-3.11
218	D	D	0.36	0.36
219	F	F	-0.19	-0.19
220	S	S	3.33	3.33
221	G	G	-2.61	-2.61
222	K	K	2.78	2.78
223	E	E	4.55	4.55
224	A	A	-0.07	-0.07
225	N	N	7.87	7.87
226	A	A	1.81	1.81
227	F	F	7.5	7.5
228	S	S	0.77	0.77
229	K	K	5.7	5.7
230	N	N	2.72	2.72
231	F	F	-2.61	-2.61
232	I	I	-3.34	-3.34
233	F	F	-5.64	-5.64
234	S	S	-0.38	-0.38
235	N	N	-1.39	-1.39
236	G	G	-2.23	-2.23
237	L	L	1.3	1.3
238	I	I	0.7	0.7
239	H	H	0.84	0.84
240	D	D	3.01	3.01
241	E	E	3.8	3.8
242	V	V	-2.69	-2.69
243	V	V	-1.72	-1.72
244	K	K	4.23	4.23
245	V	V	2.14	2.14
246	V	V	-1.06	-1.06
247	N	N	-0.37	-0.37
248	E	E	-0.36	-0.36
249	V	V	1.45	1.45
250	V	V	6.34	6.34
251	E	E	1.06	1.06
252	E	E	0.18	0.18
253	I	I	4.77	4.77
254	G	G	2.87	2.87
255	M	M	16.33	16.33
256	D	D	6.06	6.06
257	R	R	1.55	1.55
258	L	L	-1.6	-1.6
259	D	D	-1.02	-1.02
260	F	F	-2.73	-2.73
261	S	S	-1.97	-1.97
262	I	I	-5.13	-5.13
263	K	K	-2.67	-2.67
264	L	L	4.55	4.55
265	L	L	1.01	1.01
266	R	R	-2.85	-2.85
267	K	K	-2.39	-2.39
268	V	V	-2.91	-2.91
269	G	G	-1.13	-1.13
270	H	H	-1.07	-1.07
271	L	L	-0.4	-0.4
272	L	L	-4.28	-4.28
273	M	M	-0.74	-0.74
274	I	I	-1.41	-1.41
275	H	H	-2.6	-2.6
276	W	W	-1.4	-1.4
277	G	G	-1.76	-1.76
278	R	R	10.5	10.5
279	V	V	0.76	0.76
280	D	D	3.42	3.42
281	N	N	3.51	3.51
282	V	V	0.54	0.54
283	E	E	1.71	1.71
284	K	K	7.54	7.54
285	K	K	6.0	6.0
286	T	T	1.78	1.78
287	G	G	2.27	2.27
288	F	F	3.82	3.82
289	K	K	-1.11	-1.11
290	D	D	1.4	1.4
291	I	I	-1.7	-1.7
292	V	V	2.28	2.28
293	T	T	0.42	0.42
294	E	E	5.58	5.58
295	I	I	-0.64	-0.64
296	D	D	1.5	1.5
297	R	R	3.8	3.8
298	E	E	-0.52	-0.52
299	A	A	-3.23	-3.23
300	Q	Q	-0.54	-0.54
301	R	R	3.15	3.15
302	M	M	10.16	10.16
303	I	I	-5.29	-5.29
304	V	V	-2.41	-2.41
305	D	D	-1.55	-1.55
306	E	E	8.64	8.64
307	I	I	-6.27	-6.27
308	R	R	0.86	0.86
309	K	K	1.22	1.22
310	F	F	1.28	1.28
311	F	F	0.59	0.59
312	P	P	2.34	2.34
313	D	D	0.2	0.2
314	E	E	-3.1	-3.1
315	N	N	0.39	0.39
316	I	I	-5.75	-5.75
317	M	M	7.13	7.13
318	A	A	-0.62	-0.62
319	E	E	9.46	9.46
320	E	E	7.18	7.18
321	G	G	0.37	0.37
322	I	I	3.99	3.99
323	F	F	8.71	8.71
324	E	E	-1.82	-1.82
325	K	K	4.92	4.92
326	G	G	0.86	0.86
327	D	D	-0.41	-0.41
328	R	R	6.99	6.99
329	L	L	0.87	0.87
330	W	W	-5.21	-5.21
331	I	I	-3.54	-3.54
332	I	I	-1.19	-1.19
333	D	D	10.0	10.0
334	P	P	4.08	4.08
335	I	I	-0.09	-0.09
336	D	D	1.55	1.55
337	G	G	-1.28	-1.28
338	T	T	0.67	0.67
339	I	I	-1.05	-1.05
340	N	N	-1.71	-1.71
341	F	F	-5.6	-5.6
342	V	V	-2.53	-2.53
343	H	H	2.51	2.51
344	G	G	-3.35	-3.35
345	L	L	-2.58	-2.58
346	P	P	-3.71	-3.71
347	N	N	-1.11	-1.11
348	F	F	-3.63	-3.63
349	S	S	-2.94	-2.94
350	I	I	-3.52	-3.52
351	S	S	-2.12	-2.12
352	L	L	-2.55	-2.55
353	A	A	-3.04	-3.04
354	Y	Y	-3.05	-3.05
355	V	V	-0.74	-0.74
356	E	E	2.21	2.21
357	N	N	0.42	0.42
358	G	G	-1.84	-1.84
359	E	E	19.08	19.08
360	V	V	4.65	4.65
361	K	K	2.56	2.56
362	L	L	-0.24	-0.24
363	G	G	-0.77	-0.77
364	V	V	-4.43	-4.43
365	V	V	-5.55	-5.55
366	H	H	-2.57	-2.57
367	A	A	-0.33	-0.33
368	P	P	-0.05	-0.05
369	A	A	-2.65	-2.65
370	L	L	-0.26	-0.26
371	N	N	-0.72	-0.72
372	E	E	-1.65	-1.65
373	T	T	-1.05	-1.05
374	L	L	-3.37	-3.37
375	Y	Y	-5.78	-5.78
376	A	A	-3.99	-3.99
377	E	E	1.24	1.24
378	E	E	3.67	3.67
379	G	G	-1.52	-1.52
380	S	S	0.25	0.25
381	G	G	-2.64	-2.64
382	A	A	-3.31	-3.31
383	F	F	-3.31	-3.31
384	F	F	3.54	3.54
385	N	N	-3.82	-3.82
386	G	G	-1.73	-1.73
387	E	E	-0.36	-0.36
388	R	R	-0.67	-0.67
389	I	I	-2.14	-2.14
390	R	R	10.14	10.14
391	V	V	-0.59	-0.59
392	S	S	1.08	1.08
393	E	E	0.14	0.14
394	N	N	4.52	4.52
395	A	A	0.82	0.82
396	S	S	3.24	3.24
397	L	L	7.43	7.43
398	E	E	8.98	8.98
399	E	E	4.02	4.02
400	C	C	1.61	1.61
401	V	V	-3.18	-3.18
402	G	G	-2.01	-2.01
403	S	S	-2.2	-2.2
404	T	T	-0.98	-0.98
405	G	G	-0.44	-0.44
406	S	S	2.78	2.78
407	Y	Y	4.7	4.7
408	V	V	2.78	2.78
409	D	D	4.38	4.38
410	F	F	1.06	1.06
411	T	T	-0.09	-0.09
412	G	G	0.12	0.12
413	K	K	0.74	0.74
414	F	F	-6.03	-6.03
415	I	I	2.01	2.01
416	E	E	2.28	2.28
417	R	R	15.56	15.56
418	M	M	-1.04	-1.04
419	E	E	-0.42	-0.42
420	K	K	0.79	0.79
421	R	R	20.86	20.86
422	T	T	0.28	0.28
423	R	R	3.03	3.03
424	R	R	5.92	5.92
425	I	I	-0.46	-0.46
426	R	R	1.58	1.58
427	I	I	-2.04	-2.04
428	L	L	0.12	0.12
429	G	G	2.28	2.28
430	S	S	0.96	0.96
431	A	A	-0.9	-0.9
432	A	A	-2.49	-2.49
433	L	L	-2.45	-2.45
434	N	N	5.8	5.8
435	A	A	-2.62	-2.62
436	A	A	-3.9	-3.9
437	Y	Y	-0.71	-0.71
438	V	V	-3.27	-3.27
439	G	G	-0.74	-0.74
440	A	A	-1.26	-1.26
441	G	G	-1.65	-1.65
442	R	R	-2.63	-2.63
443	V	V	-1.15	-1.15
444	D	D	-0.93	-0.93
445	F	F	-3.72	-3.72
446	F	F	-3.63	-3.63
447	V	V	-5.3	-5.3
448	T	T	5.42	5.42
449	W	W	7.65	7.65
450	R	R	43.38	43.38
451	I	I	5.6	5.6
452	N	N	2.28	2.28
453	P	P	3.36	3.36
454	W	W	4.46	4.46
455	D	D	2.31	2.31
456	I	I	2.46	2.46
457	A	A	-1.17	-1.17
458	A	A	-2.85	-2.85
459	G	G	-1.18	-1.18
460	L	L	1.37	1.37
461	I	I	-1.7	-1.7
462	I	I	-5.75	-5.75
463	V	V	-5.14	-5.14
464	K	K	6.37	6.37
465	E	E	-3.33	-3.33
466	A	A	-2.33	-2.33
467	G	G	-2.64	-2.64
468	G	G	-2.2	-2.2
469	M	M	17.69	17.69
470	V	V	-0.83	-0.83
471	T	T	-2.78	-2.78
472	D	D	5.3	5.3
473	F	F	3.56	3.56
474	S	S	1.23	1.23
475	G	G	-1.87	-1.87
476	K	K	3.51	3.51
477	E	E	2.24	2.24
478	A	A	0.71	0.71
479	N	N	6.92	6.92
480	A	A	3.03	3.03
481	F	F	11.11	11.11
482	S	S	8.44	8.44
483	K	K	39.09	39.09
484	N	N	11.26	11.26
485	F	F	2.22	2.22
486	I	I	0.11	0.11
487	F	F	-6.12	-6.12
488	S	S	-2.42	-2.42
489	N	N	-2.02	-2.02
490	G	G	-1.27	-1.27
491	L	L	-1.26	-1.26
492	I	I	-1.62	-1.62
493	H	H	0.81	0.81
494	D	D	1.1	1.1
495	E	E	2.46	2.46
496	V	V	-4.99	-4.99
497	V	V	1.23	1.23
498	K	K	14.64	14.64
499	V	V	5.98	5.98
500	V	V	-3.59	-3.59
501	N	N	9.74	9.74
502	E	E	3.09	3.09
503	V	V	3.51	3.51
504	V	V	6.62	6.62
505	E	E	8.11	8.11
506	E	E	0.9	0.9
507	I	I	11.1	11.1
508	G	G	5.67	5.67
509	X	X	3.93	3.93
510	X	X	2.12	2.12
511	M	M	9.91	9.91
512	D	D	1.46	1.46
513	R	R	2.39	2.39
514	L	L	0.39	0.39
515	D	D	-3.5	-3.5
516	F	F	-3.37	-3.37
517	S	S	-1.2	-1.2
518	I	I	-4.18	-4.18
519	K	K	-2.77	-2.77
520	L	L	-2.92	-2.92
521	L	L	-1.9	-1.9
522	R	R	-3.2	-3.2
523	K	K	-1.61	-1.61
524	V	V	-2.5	-2.5
525	G	G	-0.96	-0.96
526	H	H	-0.76	-0.76
527	L	L	2.09	2.09
528	L	L	-4.0	-4.0
529	M	M	-2.09	-2.09
530	I	I	-2.14	-2.14
531	H	H	-0.34	-0.34
532	W	W	-0.68	-0.68
533	G	G	0.5	0.5
534	R	R	2.37	2.37
535	V	V	1.95	1.95
536	D	D	0.46	0.46
537	N	N	1.11	1.11
538	V	V	5.58	5.58
539	E	E	2.2	2.2
540	K	K	-0.47	-0.47
541	K	K	1.44	1.44
542	T	T	4.53	4.53
543	G	G	1.87	1.87
544	F	F	4.42	4.42
545	K	K	3.33	3.33
546	D	D	4.1	4.1
547	I	I	5.2	5.2
548	V	V	0.44	0.44
549	T	T	1.42	1.42
550	E	E	1.14	1.14
551	I	I	-3.77	-3.77
552	D	D	1.22	1.22
553	R	R	5.55	5.55
554	E	E	-1.3	-1.3
555	A	A	-2.51	-2.51
556	Q	Q	0.16	0.16
557	R	R	5.66	5.66
558	M	M	1.47	1.47
559	I	I	-4.94	-4.94
560	V	V	-2.87	-2.87
561	D	D	2.79	2.79
562	E	E	2.58	2.58
563	I	I	-4.4	-4.4
564	R	R	2.67	2.67
565	K	K	1.45	1.45
566	F	F	1.03	1.03
567	F	F	3.28	3.28
568	P	P	6.83	6.83
569	D	D	2.29	2.29
570	E	E	-2.9	-2.9
571	N	N	-2.98	-2.98
572	I	I	-1.56	-1.56
573	M	M	6.54	6.54
574	A	A	1.83	1.83
575	E	E	0.9	0.9
576	E	E	1.88	1.88
577	G	G	-2.02	-2.02
578	I	I	0.29	0.29
579	F	F	1.78	1.78
580	E	E	-0.36	-0.36
581	K	K	3.29	3.29
582	G	G	-1.34	-1.34
583	D	D	0.28	0.28
584	R	R	3.25	3.25
585	L	L	-0.76	-0.76
586	W	W	-6.2	-6.2
587	I	I	-3.8	-3.8
588	I	I	-5.03	-5.03
589	D	D	4.57	4.57
590	P	P	-1.32	-1.32
591	I	I	1.06	1.06
592	D	D	1.38	1.38
593	G	G	-1.29	-1.29
594	T	T	1.04	1.04
595	I	I	2.4	2.4
596	N	N	-3.31	-3.31
597	F	F	-5.57	-5.57
598	V	V	-3.38	-3.38
599	H	H	1.27	1.27
600	G	G	-3.39	-3.39
601	L	L	-1.47	-1.47
602	P	P	0.24	0.24
603	N	N	4.05	4.05
604	F	F	-4.91	-4.91
605	S	S	-3.13	-3.13
606	I	I	-0.09	-0.09
607	S	S	-1.46	-1.46
608	L	L	-2.97	-2.97
609	A	A	-3.38	-3.38
610	Y	Y	-4.55	-4.55
611	V	V	-2.79	-2.79
612	E	E	16.64	16.64
613	N	N	0.8	0.8
614	G	G	-2.46	-2.46
615	E	E	2.91	2.91
616	V	V	-1.77	-1.77
617	K	K	8.58	8.58
618	L	L	0.96	0.96
619	G	G	-0.17	-0.17
620	V	V	-3.44	-3.44
621	V	V	-5.45	-5.45
622	H	H	-0.46	-0.46
623	A	A	0.62	0.62
624	P	P	1.1	1.1
625	A	A	-2.75	-2.75
626	L	L	-0.52	-0.52
627	N	N	1.8	1.8
628	E	E	-1.5	-1.5
629	T	T	-1.45	-1.45
630	L	L	-3.12	-3.12
631	Y	Y	-5.5	-5.5
632	A	A	-3.67	-3.67
633	E	E	0.65	0.65
634	E	E	2.76	2.76
635	G	G	-1.69	-1.69
636	S	S	0.34	0.34
637	G	G	-2.45	-2.45
638	A	A	-3.35	-3.35
639	F	F	-2.09	-2.09
640	F	F	0.29	0.29
641	N	N	-4.1	-4.1
642	G	G	-1.52	-1.52
643	E	E	-0.74	-0.74
644	R	R	1.41	1.41
645	I	I	-0.63	-0.63
646	R	R	3.56	3.56
647	V	V	-0.55	-0.55
648	S	S	0.84	0.84
649	E	E	0.75	0.75
650	N	N	-0.27	-0.27
651	A	A	0.32	0.32
652	S	S	2.85	2.85
653	L	L	-0.06	-0.06
654	E	E	4.02	4.02
655	E	E	3.08	3.08
656	C	C	0.33	0.33
657	V	V	-1.68	-1.68
658	G	G	-1.44	-1.44
659	S	S	-0.85	-0.85
660	T	T	-3.04	-3.04
661	G	G	1.17	1.17
662	S	S	3.26	3.26
663	Y	Y	1.8	1.8
664	V	V	2.11	2.11
665	D	D	6.46	6.46
666	F	F	0.42	0.42
667	T	T	0.12	0.12
668	G	G	-0.01	-0.01
669	K	K	3.54	3.54
670	F	F	-5.09	-5.09
671	I	I	-0.63	-0.63
672	E	E	6.49	6.49
673	R	R	10.05	10.05
674	M	M	14.57	14.57
675	E	E	11.99	11.99
676	K	K	4.91	4.91
677	R	R	4.09	4.09
678	T	T	12.96	12.96
679	R	R	7.05	7.05
680	R	R	7.03	7.03
681	I	I	0.91	0.91
682	R	R	3.97	3.97
683	I	I	-3.45	-3.45
684	L	L	-0.46	-0.46
685	G	G	0.07	0.07
686	S	S	6.58	6.58
687	A	A	1.84	1.84
688	A	A	-2.89	-2.89
689	L	L	-3.37	-3.37
690	N	N	5.3	5.3
691	A	A	-3.13	-3.13
692	A	A	-3.15	-3.15
693	Y	Y	-0.91	-0.91
694	V	V	-2.44	-2.44
695	G	G	-0.82	-0.82
696	A	A	0.42	0.42
697	G	G	-1.52	-1.52
698	R	R	-2.27	-2.27
699	V	V	-0.63	-0.63
700	D	D	-4.01	-4.01
701	F	F	-1.8	-1.8
702	F	F	-3.5	-3.5
703	V	V	-5.26	-5.26
704	T	T	-0.71	-0.71
705	W	W	0.65	0.65
706	R	R	9.11	9.11
707	I	I	0.0	0.0
708	N	N	3.71	3.71
709	P	P	1.86	1.86
710	W	W	-0.4	-0.4
711	D	D	1.56	1.56
712	I	I	-1.34	-1.34
713	A	A	-2.32	-2.32
714	A	A	-1.99	-1.99
715	G	G	-1.32	-1.32
716	L	L	19.63	19.63
717	I	I	-0.46	-0.46
718	I	I	-4.4	-4.4
719	V	V	-4.5	-4.5
720	K	K	-2.64	-2.64
721	E	E	-3.01	-3.01
722	A	A	-3.6	-3.6
723	G	G	-2.56	-2.56
724	G	G	-1.77	-1.77
725	M	M	1.0	1.0
726	V	V	-3.82	-3.82
727	T	T	-4.24	-4.24
728	D	D	4.65	4.65
729	F	F	-1.17	-1.17
730	S	S	-0.07	-0.07
731	G	G	-2.19	-2.19
732	K	K	1.08	1.08
733	E	E	0.28	0.28
734	A	A	-3.16	-3.16
735	N	N	0.39	0.39
736	A	A	-1.57	-1.57
737	F	F	0.38	0.38
738	S	S	-0.16	-0.16
739	K	K	0.42	0.42
740	N	N	13.09	13.09
741	F	F	-3.22	-3.22
742	I	I	-3.05	-3.05
743	F	F	-5.48	-5.48
744	S	S	-2.34	-2.34
745	N	N	-1.46	-1.46
746	G	G	-1.66	-1.66
747	L	L	0.25	0.25
748	I	I	2.09	2.09
749	H	H	-0.69	-0.69
750	D	D	0.59	0.59
751	E	E	4.66	4.66
752	V	V	-3.57	-3.57
753	V	V	-1.73	-1.73
754	K	K	0.52	0.52
755	V	V	7.48	7.48
756	V	V	0.86	0.86
757	N	N	11.57	11.57
758	E	E	0.6	0.6
759	V	V	-3.65	-3.65
760	V	V	3.01	3.01
761	E	E	14.53	14.53
762	E	E	2.31	2.31
763	I	I	12.79	12.79
764	G	G	7.37	7.37
765	X	X	3.9	3.9
766	M	M	12.07	12.07
767	D	D	3.35	3.35
768	R	R	3.34	3.34
769	L	L	6.54	6.54
770	D	D	-2.44	-2.44
771	F	F	0.25	0.25
772	S	S	-0.53	-0.53
773	I	I	-0.79	-0.79
774	K	K	-1.84	-1.84
775	L	L	-2.52	-2.52
776	L	L	3.86	3.86
777	R	R	-3.34	-3.34
778	K	K	-0.39	-0.39
779	V	V	1.28	1.28
780	G	G	-1.13	-1.13
781	H	H	0.97	0.97
782	L	L	15.02	15.02
783	L	L	-2.86	-2.86
784	M	M	-1.8	-1.8
785	I	I	1.98	1.98
786	H	H	-0.85	-0.85
787	W	W	-1.81	-1.81
788	G	G	-1.75	-1.75
789	R	R	6.53	6.53
790	V	V	10.77	10.77
791	D	D	7.18	7.18
792	N	N	12.11	12.11
793	V	V	5.95	5.95
794	E	E	6.64	6.64
795	K	K	21.52	21.52
796	K	K	8.15	8.15
797	T	T	4.37	4.37
798	G	G	3.18	3.18
799	F	F	18.85	18.85
800	K	K	3.97	3.97
801	D	D	5.9	5.9
802	I	I	12.75	12.75
803	V	V	3.44	3.44
804	T	T	3.98	3.98
805	E	E	2.88	2.88
806	I	I	3.32	3.32
807	D	D	1.94	1.94
808	R	R	4.11	4.11
809	E	E	10.03	10.03
810	A	A	-3.34	-3.34
811	Q	Q	-0.65	-0.65
812	R	R	4.19	4.19
813	M	M	10.3	10.3
814	I	I	-2.88	-2.88
815	V	V	0.06	0.06
816	D	D	-0.12	-0.12
817	E	E	-2.0	-2.0
818	I	I	-4.11	-4.11
819	R	R	3.99	3.99
820	K	K	4.02	4.02
821	F	F	0.06	0.06
822	F	F	4.35	4.35
823	P	P	10.58	10.58
824	D	D	2.26	2.26
825	E	E	-2.32	-2.32
826	N	N	0.78	0.78
827	I	I	-0.05	-0.05
828	M	M	3.48	3.48
829	A	A	-0.66	-0.66
830	E	E	8.2	8.2
831	E	E	4.0	4.0
832	G	G	0.12	0.12
833	I	I	9.16	9.16
834	F	F	6.44	6.44
835	E	E	4.77	4.77
836	K	K	12.6	12.6
837	G	G	1.31	1.31
838	D	D	13.34	13.34
839	R	R	2.51	2.51
840	L	L	-2.71	-2.71
841	W	W	-3.79	-3.79
842	I	I	-3.29	-3.29
843	I	I	0.22	0.22
844	D	D	6.42	6.42
845	P	P	-0.55	-0.55
846	I	I	-0.6	-0.6
847	D	D	-0.08	-0.08
848	G	G	-1.49	-1.49
849	T	T	0.65	0.65
850	I	I	1.34	1.34
851	N	N	-2.77	-2.77
852	F	F	-5.64	-5.64
853	V	V	-1.4	-1.4
854	H	H	2.49	2.49
855	G	G	-3.58	-3.58
856	L	L	0.33	0.33
857	P	P	-2.83	-2.83
858	N	N	-0.55	-0.55
859	F	F	-5.56	-5.56
860	S	S	-2.84	-2.84
861	I	I	-2.73	-2.73
862	S	S	-0.96	-0.96
863	L	L	-1.3	-1.3
864	A	A	-3.03	-3.03
865	Y	Y	-2.05	-2.05
866	V	V	-2.31	-2.31
867	E	E	2.45	2.45
868	N	N	3.73	3.73
869	G	G	-1.65	-1.65
870	E	E	4.53	4.53
871	V	V	4.68	4.68
872	K	K	2.5	2.5
873	L	L	0.34	0.34
874	G	G	0.16	0.16
875	V	V	1.07	1.07
876	V	V	-5.22	-5.22
877	H	H	-0.54	-0.54
878	A	A	-0.89	-0.89
879	P	P	0.83	0.83
880	A	A	-2.6	-2.6
881	L	L	-1.78	-1.78
882	N	N	0.29	0.29
883	E	E	-0.85	-0.85
884	T	T	1.42	1.42
885	L	L	-3.82	-3.82
886	Y	Y	-1.51	-1.51
887	A	A	-3.83	-3.83
888	E	E	7.62	7.62
889	E	E	2.84	2.84
890	G	G	-1.55	-1.55
891	S	S	0.97	0.97
892	G	G	0.72	0.72
893	A	A	-2.29	-2.29
894	F	F	0.56	0.56
895	F	F	2.36	2.36
896	N	N	-4.11	-4.11
897	G	G	-1.54	-1.54
898	E	E	1.28	1.28
899	R	R	12.87	12.87
900	I	I	2.29	2.29
901	R	R	2.75	2.75
902	V	V	2.1	2.1
903	S	S	1.34	1.34
904	E	E	0.48	0.48
905	N	N	2.94	2.94
906	A	A	1.28	1.28
907	S	S	3.2	3.2
908	L	L	1.72	1.72
909	E	E	3.56	3.56
910	E	E	3.95	3.95
911	C	C	-0.29	-0.29
912	V	V	0.08	0.08
913	G	G	-1.54	-1.54
914	S	S	-1.66	-1.66
915	T	T	2.34	2.34
916	G	G	-0.52	-0.52
917	S	S	1.47	1.47
918	Y	Y	1.9	1.9
919	V	V	9.75	9.75
920	D	D	-0.1	-0.1
921	F	F	-1.42	-1.42
922	T	T	-1.11	-1.11
923	G	G	-0.8	-0.8
924	K	K	4.91	4.91
925	F	F	-4.66	-4.66
926	I	I	4.08	4.08
927	E	E	4.55	4.55
928	R	R	7.66	7.66
929	M	M	2.16	2.16
930	E	E	15.62	15.62
931	K	K	12.02	12.02
932	R	R	14.44	14.44
933	T	T	5.5	5.5
934	R	R	3.67	3.67
935	R	R	15.57	15.57
936	I	I	-1.0	-1.0
937	R	R	8.04	8.04
938	I	I	-2.3	-2.3
939	L	L	-1.37	-1.37
940	G	G	-0.83	-0.83
941	S	S	0.18	0.18
942	A	A	-0.05	-0.05
943	A	A	-3.19	-3.19
944	L	L	-2.58	-2.58
945	N	N	4.59	4.59
946	A	A	-3.44	-3.44
947	A	A	-4.22	-4.22
948	Y	Y	-1.96	-1.96
949	V	V	1.74	1.74
950	G	G	-0.73	-0.73
951	A	A	1.76	1.76
952	G	G	-1.45	-1.45
953	R	R	1.2	1.2
954	V	V	2.74	2.74
955	D	D	-0.74	-0.74
956	F	F	-4.43	-4.43
957	F	F	-2.22	-2.22
958	V	V	-3.93	-3.93
959	T	T	3.16	3.16
960	W	W	1.62	1.62
961	R	R	2.82	2.82
962	I	I	2.53	2.53
963	N	N	9.18	9.18
964	P	P	-0.15	-0.15
965	W	W	5.19	5.19
966	D	D	8.12	8.12
967	I	I	5.84	5.84
968	A	A	-1.61	-1.61
969	A	A	-2.48	-2.48
970	G	G	-1.31	-1.31
971	L	L	3.09	3.09
972	I	I	-1.32	-1.32
973	I	I	-6.19	-6.19
974	V	V	-1.48	-1.48
975	K	K	5.78	5.78
976	E	E	-1.91	-1.91
977	A	A	-3.46	-3.46
978	G	G	-2.46	-2.46
979	G	G	-0.38	-0.38
980	M	M	2.43	2.43
981	V	V	0.44	0.44
982	T	T	-3.67	-3.67
983	D	D	-0.06	-0.06
984	F	F	2.47	2.47
985	S	S	1.77	1.77
986	G	G	-2.47	-2.47
987	K	K	2.39	2.39
988	E	E	6.93	6.93
989	A	A	-0.55	-0.55
990	N	N	-0.12	-0.12
991	A	A	0.6	0.6
992	F	F	3.07	3.07
993	S	S	-0.87	-0.87
994	K	K	31.6	31.6
995	N	N	13.12	13.12
996	F	F	-2.65	-2.65
997	I	I	-3.71	-3.71
998	F	F	-0.96	-0.96
999	S	S	-2.12	-2.12
1000	N	N	0.63	0.63
1001	G	G	-2.15	-2.15
1002	L	L	3.3	3.3
1003	I	I	3.14	3.14
1004	H	H	1.17	1.17
1005	D	D	-1.0	-1.0
1006	E	E	2.68	2.68
1007	V	V	-4.22	-4.22
1008	V	V	-0.54	-0.54
1009	K	K	1.32	1.32
1010	V	V	0.04	0.04
1011	V	V	-1.79	-1.79
1012	N	N	0.46	0.46
1013	E	E	-1.98	-1.98
1014	V	V	1.3	1.3
1015	V	V	5.94	5.94
1016	E	E	3.73	3.73
1017	E	E	0.22	0.22
1018	I	I	3.6	3.6
1019	G	G	3.96	3.96
1020	X	X	2.9	2.9

Analysis of pair 2p3vD_2p3vA

Figure 1: Two structures (Fold1 & Fold2)

Figure 2: Two structures aligned

Figure 3: Deep-MSA contact map panel

Figure 4: Best clusters contact map panel

Figure 5: All clusters contact-map mosaic (small multiples).

Per-cluster contact maps

Figure 6: Aligned per-residue ΔΔG (seq alignment overlay).

Figure 7: Phylogenetic tree with per-cluster heatmap.

Cluster metrics table

Aligned per-residue ΔΔG