Analysis of 4zrbH

cluster	n	neff	AF2_TM1	AF2_TM2	AF3_TM1	AF3_TM2	RE-MSAT-COM	RE-MSAT1	RE-MSAT2	ESM_SEQIDS	ESM_TM1_LIST	ESM_TM2_LIST
Deep	-	-	0.99	0.99	0.99	0.99	0.56	0.56	0.53	-	-	-
000	-	-	0.96	0.96	0.91	0.91	0.22	0.22	0.22	007; 007; 001; 001; 004; 008; 004; 008; 003; 003	0.88; 0.88; 0.87; 0.87; 0.85; 0.85; 0.85; 0.85; 0.84; 0.84	0.88; 0.88; 0.87; 0.87; 0.85; 0.85; 0.85; 0.85; 0.84; 0.84
001	-	-	0.86	0.86	0.85	0.85	0.24	0.24	0.23	002; 002; 005; 005; 001; 001; 004; 004; 008; 008	0.90; 0.90; 0.87; 0.87; 0.86; 0.86; 0.85; 0.85; 0.83; 0.83	0.90; 0.90; 0.87; 0.87; 0.86; 0.86; 0.85; 0.85; 0.83; 0.83
002	-	-	0.87	0.87	0.87	0.87	0.22	0.22	0.22	004; 003; 003; 004; 007; 002; 006; 007; 002; 006	0.88; 0.88; 0.88; 0.88; 0.86; 0.86; 0.86; 0.86; 0.86; 0.86	0.88; 0.88; 0.88; 0.88; 0.86; 0.86; 0.86; 0.86; 0.86; 0.86
003	-	-	0.79	0.79	0.81	0.81	0.01	0.01	0.02	004; 004; 001; 001; 005; 005; 010; 010; 002; 002	0.88; 0.88; 0.85; 0.85; 0.84; 0.84; 0.83; 0.83; 0.82; 0.82	0.88; 0.88; 0.85; 0.85; 0.84; 0.84; 0.83; 0.83; 0.82; 0.82
004	-	-	0.55	0.55	0.61	0.61	0.12	0.11	0.1	001; 001; 009; 003; 009; 003; 005; 005; 004; 002	0.87; 0.87; 0.85; 0.85; 0.85; 0.85; 0.84; 0.84; 0.83; 0.83	0.87; 0.87; 0.85; 0.85; 0.85; 0.85; 0.84; 0.84; 0.83; 0.83
005	-	-	0.86	0.86	0.87	0.87	0.47	0.46	0.44	002; 003; 002; 008; 008; 003; 001; 001; 010; 010	0.87; 0.87; 0.87; 0.87; 0.87; 0.87; 0.86; 0.86; 0.84; 0.84	0.87; 0.87; 0.87; 0.87; 0.87; 0.87; 0.86; 0.86; 0.84; 0.84
006	-	-	0.58	0.58	0.59	0.59	0.01	0.01	0.02	001; 001; 003; 003; 004; 002; 004; 002; 010; 010	0.87; 0.87; 0.86; 0.86; 0.85; 0.85; 0.85; 0.85; 0.84; 0.84	0.87; 0.87; 0.86; 0.86; 0.85; 0.85; 0.85; 0.85; 0.84; 0.84
007	-	-	0.86	0.86	0.81	0.81	0.01	0.01	0.02	005; 005; 006; 006; 008; 008; 001; 001; 003; 003	0.87; 0.87; 0.86; 0.86; 0.84; 0.84; 0.84; 0.84; 0.83; 0.83	0.87; 0.87; 0.86; 0.86; 0.84; 0.84; 0.84; 0.84; 0.83; 0.83
008	-	-	0.82	0.82	0.79	0.79	0.04	0.05	0.05	010; 010; 003; 003; 002; 002; 001; 001; 004; 005	0.90; 0.90; 0.89; 0.89; 0.87; 0.87; 0.87; 0.87; 0.85; 0.85	0.90; 0.90; 0.89; 0.89; 0.87; 0.87; 0.87; 0.87; 0.85; 0.85
009	-	-	0.79	0.79	0.76	0.76	0.0	0.0	0.01	008; 008; 007; 007; 001; 002; 002; 001; 003; 003	0.88; 0.88; 0.85; 0.85; 0.84; 0.84; 0.84; 0.84; 0.67; 0.67	0.88; 0.88; 0.85; 0.85; 0.84; 0.84; 0.84; 0.84; 0.67; 0.67
010	-	-	0.81	0.81	0.79	0.79	0.05	0.06	0.05	004; 004; 006; 003; 003; 006; 007; 001; 001; 007	0.84; 0.84; 0.79; 0.79; 0.79; 0.79; 0.78; 0.78; 0.78; 0.78	0.84; 0.84; 0.79; 0.79; 0.79; 0.79; 0.78; 0.78; 0.78; 0.78
011	-	-	0.87	0.87	0.84	0.84	0.33	0.32	0.3	007; 007; 001; 002; 003; 003; 001; 002; 004; 010	0.88; 0.88; 0.87; 0.87; 0.87; 0.87; 0.87; 0.87; 0.85; 0.85	0.88; 0.88; 0.87; 0.87; 0.87; 0.87; 0.87; 0.87; 0.85; 0.85
012	-	-	0.72	0.72	0.72	0.72	0.09	0.08	0.08	005; 005; 002; 002; 006; 006; 001; 004; 001; 004	0.88; 0.88; 0.87; 0.87; 0.87; 0.87; 0.85; 0.85; 0.85; 0.85	0.88; 0.88; 0.87; 0.87; 0.87; 0.87; 0.85; 0.85; 0.85; 0.85
013	-	-	0.98	0.98	0.99	0.99	0.41	0.4	0.37	001; 001; 003; 002; 003; 002; 004; 006; 009; 006	0.93; 0.93; 0.89; 0.89; 0.89; 0.89; 0.86; 0.86; 0.86; 0.86	0.93; 0.93; 0.89; 0.89; 0.89; 0.89; 0.86; 0.86; 0.86; 0.86
014	-	-	0.76	0.76	0.8	0.8	0.02	0.02	0.02	002; 004; 007; 005; 005; 007; 002; 004; 001; 001	0.87; 0.87; 0.87; 0.87; 0.87; 0.87; 0.87; 0.87; 0.86; 0.86	0.87; 0.87; 0.87; 0.87; 0.87; 0.87; 0.87; 0.87; 0.86; 0.86
015	-	-	0.76	0.76	0.65	0.65	0.46	0.46	0.42	001; 001; 003; 002; 003; 002; 004; 006; 010; 006	0.87; 0.87; 0.86; 0.86; 0.86; 0.86; 0.85; 0.85; 0.85; 0.85	0.87; 0.87; 0.86; 0.86; 0.86; 0.86; 0.85; 0.85; 0.85; 0.85
016	-	-	0.74	0.74	0.75	0.75	0.02	0.02	0.04	003; 003; 001; 001; 004; 004; 006; 006; 002; 002	0.88; 0.88; 0.87; 0.87; 0.85; 0.85; 0.84; 0.84; 0.82; 0.82	0.88; 0.88; 0.87; 0.87; 0.85; 0.85; 0.84; 0.84; 0.82; 0.82
017	-	-	0.82	0.82	0.73	0.73	0.02	0.02	0.01	003; 007; 003; 007; 001; 001; 004; 004; 008; 008	0.89; 0.89; 0.89; 0.89; 0.88; 0.88; 0.87; 0.87; 0.87; 0.87	0.89; 0.89; 0.89; 0.89; 0.88; 0.88; 0.87; 0.87; 0.87; 0.87
018	-	-	0.85	0.85	0.85	0.85	0.02	0.02	0.02	006; 007; 006; 005; 007; 005; 004; 004; 001; 001	0.88; 0.88; 0.88; 0.87; 0.87; 0.87; 0.85; 0.85; 0.84; 0.84	0.88; 0.88; 0.88; 0.87; 0.87; 0.87; 0.85; 0.85; 0.84; 0.84
019	-	-	0.82	0.82	0.81	0.81	0.0	0.0	0.0	005; 005; 001; 001; 009; 009; 004; 007; 004; 007	0.87; 0.87; 0.86; 0.86; 0.86; 0.86; 0.85; 0.85; 0.85; 0.85	0.87; 0.87; 0.86; 0.86; 0.86; 0.86; 0.85; 0.85; 0.85; 0.85
020	-	-	0.96	0.96	0.96	0.96	0.24	0.24	0.24	002; 003; 003; 002; 001; 001; 005; 005; 004; 004	0.88; 0.88; 0.88; 0.88; 0.87; 0.87; 0.85; 0.85; 0.84; 0.84	0.88; 0.88; 0.88; 0.88; 0.87; 0.87; 0.85; 0.85; 0.84; 0.84

Aligned per-residue ΔΔG

aln_pos	aa1	aa2	E1	E2
1	F	F	0.29	0.29
2	H	H	1.99	1.99
3	F	F	-3.26	-3.26
4	D	D	-2.53	-2.53
5	A	A	-2.05	-2.05
6	I	I	-1.39	-1.39
7	S	S	0.18	0.18
8	A	A	-1.85	-1.85
9	F	F	-1.84	-1.84
10	E	E	2.07	2.07
11	N	N	-0.12	-0.12
12	Y	Y	-3.21	-3.21
13	E	E	-0.04	-0.04
14	I	I	-0.89	-0.89
15	E	E	-1.09	-1.09
16	K	K	-0.21	-0.21
17	M	M	1.22	1.22
18	R	R	10.62	10.62
19	D	D	4.67	4.67
20	G	G	-2.81	-2.81
21	H	H	0.63	0.63
22	V	V	-3.52	-3.52
23	V	V	-3.2	-3.2
24	V	V	-5.17	-5.17
25	T	T	-1.78	-1.78
26	T	T	-2.13	-2.13
27	K	K	0.91	0.91
28	V	V	-4.77	-4.77
29	V	V	-0.57	-0.57
30	N	N	0.21	0.21
31	S	S	0.54	0.54
32	S	S	-0.28	-0.28
33	L	L	-4.36	-4.36
34	N	N	-2.37	-2.37
35	Y	Y	10.09	10.09
36	Y	Y	2.17	2.17
37	G	G	-2.57	-2.57
38	N	N	-2.34	-2.34
39	A	A	-3.07	-3.07
40	H	H	-4.86	-4.86
41	G	G	-0.5	-0.5
42	G	G	0.12	0.12
43	Y	Y	-2.29	-2.29
44	L	L	-5.29	-5.29
45	F	F	-5.53	-5.53
46	T	T	-2.03	-2.03
47	L	L	-4.45	-4.45
48	C	C	-1.04	-1.04
49	D	D	0.25	0.25
50	Q	Q	-3.36	-3.36
51	I	I	-1.21	-1.21
52	S	S	-1.85	-1.85
53	G	G	-0.58	-0.58
54	L	L	-2.39	-2.39
55	V	V	-3.9	-3.9
56	V	V	-1.9	-1.9
57	I	I	-1.79	-1.79
58	S	S	-2.66	-2.66
59	L	L	-3.4	-3.4
60	G	G	-2.54	-2.54
61	L	L	-2.56	-2.56
62	D	D	-0.99	-0.99
63	G	G	-1.11	-1.11
64	V	V	-2.75	-2.75
65	T	T	-1.4	-1.4
66	L	L	-2.81	-2.81
67	Q	Q	0.18	0.18
68	S	S	-2.08	-2.08
69	S	S	-0.03	-0.03
70	I	I	-4.91	-4.91
71	N	N	-2.6	-2.6
72	Y	Y	-4.57	-4.57
73	L	L	-0.99	-0.99
74	K	K	2.7	2.7
75	A	A	0.11	0.11
76	G	G	-1.5	-1.5
77	K	K	-0.97	-0.97
78	L	L	-1.06	-1.06
79	D	D	-0.06	-0.06
80	D	D	-3.11	-3.11
81	V	V	-0.4	-0.4
82	L	L	-5.78	-5.78
83	T	T	-1.35	-1.35
84	I	I	-0.67	-0.67
85	K	K	1.6	1.6
86	G	G	0.06	0.06
87	E	E	-1.83	-1.83
88	C	C	-0.85	-0.85
89	V	V	-0.38	-0.38
90	H	H	-0.28	-0.28
91	Q	Q	-0.4	-0.4
92	G	G	0.44	0.44
93	R	R	5.09	5.09
94	T	T	1.44	1.44
95	T	T	3.98	3.98
96	C	C	-1.22	-1.22
97	V	V	-4.69	-4.69
98	M	M	1.9	1.9
99	D	D	-2.04	-2.04
100	V	V	-4.54	-4.54
101	D	D	2.33	2.33
102	I	I	-5.61	-5.61
103	T	T	-2.84	-2.84
104	N	N	-3.35	-3.35
105	Q	Q	2.04	2.04
106	E	E	-0.24	-0.24
107	G	G	-2.19	-2.19
108	R	R	1.06	1.06
109	N	N	-0.23	-0.23
110	V	V	-4.5	-4.5
111	C	C	-1.81	-1.81
112	K	K	1.64	1.64
113	A	A	-2.71	-2.71
114	T	T	-2.07	-2.07
115	F	F	-3.68	-3.68
116	T	T	3.58	3.58
117	M	M	-3.05	-3.05
118	F	F	-5.25	-5.25
119	V	V	-1.43	-1.43
120	T	T	-2.28	-2.28
121	G	G	-1.92	-1.92
122	Q	Q	7.17	7.17
123	R	R	4.09	4.09
124	F	F	-0.29	-0.29
125	H	H	4.47	4.47
126	F	F	-1.81	-1.81
127	D	D	1.34	1.34
128	A	A	-1.9	-1.9
129	I	I	-1.1	-1.1
130	S	S	0.26	0.26
131	A	A	-1.86	-1.86
132	F	F	-3.45	-3.45
133	E	E	4.5	4.5
134	N	N	-0.62	-0.62
135	Y	Y	-3.26	-3.26
136	E	E	2.86	2.86
137	I	I	-1.25	-1.25
138	E	E	-0.34	-0.34
139	K	K	3.41	3.41
140	M	M	1.44	1.44
141	R	R	14.36	14.36
142	D	D	0.18	0.18
143	G	G	-3.29	-3.29
144	H	H	0.56	0.56
145	V	V	-3.6	-3.6
146	V	V	-3.06	-3.06
147	V	V	-5.21	-5.21
148	T	T	-1.48	-1.48
149	T	T	-2.09	-2.09
150	K	K	-4.0	-4.0
151	V	V	-4.89	-4.89
152	V	V	-1.05	-1.05
153	N	N	2.95	2.95
154	S	S	0.9	0.9
155	S	S	-0.35	-0.35
156	L	L	-4.17	-4.17
157	N	N	-2.1	-2.1
158	Y	Y	6.02	6.02
159	Y	Y	3.47	3.47
160	G	G	-2.28	-2.28
161	N	N	-2.94	-2.94
162	A	A	-2.99	-2.99
163	H	H	-2.58	-2.58
164	G	G	-0.65	-0.65
165	G	G	0.01	0.01
166	Y	Y	-2.19	-2.19
167	L	L	-4.93	-4.93
168	F	F	-5.44	-5.44
169	T	T	-1.97	-1.97
170	L	L	-5.07	-5.07
171	C	C	-0.65	-0.65
172	D	D	0.39	0.39
173	Q	Q	-0.45	-0.45
174	I	I	-1.07	-1.07
175	S	S	-1.63	-1.63
176	G	G	-0.71	-0.71
177	L	L	-2.89	-2.89
178	V	V	-4.02	-4.02
179	V	V	-1.82	-1.82
180	I	I	-2.12	-2.12
181	S	S	-2.46	-2.46
182	L	L	-2.91	-2.91
183	G	G	-3.21	-3.21
184	L	L	-2.74	-2.74
185	D	D	-1.11	-1.11
186	G	G	-0.89	-0.89
187	V	V	12.21	12.21
188	T	T	-1.29	-1.29
189	L	L	-1.98	-1.98
190	Q	Q	-0.33	-0.33
191	S	S	-2.25	-2.25
192	S	S	-0.19	-0.19
193	I	I	-4.67	-4.67
194	N	N	-1.43	-1.43
195	Y	Y	-4.09	-4.09
196	L	L	-1.03	-1.03
197	K	K	2.12	2.12
198	A	A	-0.11	-0.11
199	G	G	-1.41	-1.41
200	K	K	0.15	0.15
201	L	L	-0.93	-0.93
202	D	D	-0.27	-0.27
203	D	D	-3.19	-3.19
204	V	V	-0.01	-0.01
205	L	L	-5.91	-5.91
206	T	T	-2.09	-2.09
207	I	I	0.32	0.32
208	K	K	-0.69	-0.69
209	G	G	-0.05	-0.05
210	E	E	-1.71	-1.71
211	C	C	-0.99	-0.99
212	V	V	-2.09	-2.09
213	H	H	-0.99	-0.99
214	Q	Q	0.01	0.01
215	G	G	0.64	0.64
216	R	R	7.13	7.13
217	T	T	2.73	2.73
218	T	T	-1.02	-1.02
219	C	C	-1.36	-1.36
220	V	V	-5.02	-5.02
221	M	M	1.39	1.39
222	D	D	-1.46	-1.46
223	V	V	-4.26	-4.26
224	D	D	0.76	0.76
225	I	I	-5.77	-5.77
226	T	T	-2.86	-2.86
227	N	N	-3.43	-3.43
228	Q	Q	1.91	1.91
229	E	E	0.25	0.25
230	G	G	-1.99	-1.99
231	R	R	1.23	1.23
232	N	N	-1.44	-1.44
233	V	V	-3.88	-3.88
234	C	C	-0.71	-0.71
235	K	K	3.78	3.78
236	A	A	-2.81	-2.81
237	T	T	-1.59	-1.59
238	F	F	-2.81	-2.81
239	T	T	-2.34	-2.34
240	M	M	-2.94	-2.94
241	F	F	-0.7	-0.7
242	V	V	-2.66	-2.66
243	T	T	-1.47	-1.47
244	G	G	-1.87	-1.87
245	Q	Q	3.99	3.99
246	R	R	1.07	1.07
247	F	F	-0.14	-0.14
248	H	H	1.86	1.86
249	F	F	-3.13	-3.13
250	D	D	-1.93	-1.93
251	A	A	-1.91	-1.91
252	I	I	-1.13	-1.13
253	S	S	0.38	0.38
254	A	A	-1.94	-1.94
255	F	F	-1.77	-1.77
256	E	E	3.48	3.48
257	N	N	-0.52	-0.52
258	Y	Y	-3.21	-3.21
259	E	E	0.38	0.38
260	I	I	-0.81	-0.81
261	E	E	-0.86	-0.86
262	K	K	3.46	3.46
263	M	M	1.49	1.49
264	R	R	6.66	6.66
265	D	D	-0.32	-0.32
266	G	G	-3.52	-3.52
267	H	H	3.77	3.77
268	V	V	-3.66	-3.66
269	V	V	-3.38	-3.38
270	V	V	-5.33	-5.33
271	T	T	-1.78	-1.78
272	T	T	-2.2	-2.2
273	K	K	-1.75	-1.75
274	V	V	-4.71	-4.71
275	V	V	-0.48	-0.48
276	N	N	0.48	0.48
277	S	S	0.65	0.65
278	S	S	-0.23	-0.23
279	L	L	-4.43	-4.43
280	N	N	-2.04	-2.04
281	Y	Y	8.22	8.22
282	Y	Y	1.89	1.89
283	G	G	-2.35	-2.35
284	N	N	-2.9	-2.9
285	A	A	-3.15	-3.15
286	H	H	-4.79	-4.79
287	G	G	-0.57	-0.57
288	G	G	0.25	0.25
289	Y	Y	-2.29	-2.29
290	L	L	-5.28	-5.28
291	F	F	-5.43	-5.43
292	T	T	-1.94	-1.94
293	L	L	-4.82	-4.82
294	C	C	-0.98	-0.98
295	D	D	0.2	0.2
296	Q	Q	2.53	2.53
297	I	I	-0.99	-0.99
298	S	S	-1.69	-1.69
299	G	G	-0.47	-0.47
300	L	L	-3.41	-3.41
301	V	V	-4.05	-4.05
302	V	V	-1.73	-1.73
303	I	I	-2.47	-2.47
304	S	S	-2.47	-2.47
305	L	L	-3.49	-3.49
306	G	G	-2.88	-2.88
307	L	L	-2.83	-2.83
308	D	D	-1.83	-1.83
309	G	G	-0.45	-0.45
310	V	V	15.36	15.36
311	T	T	-2.07	-2.07
312	L	L	-2.71	-2.71
313	Q	Q	0.17	0.17
314	S	S	-1.96	-1.96
315	S	S	-0.03	-0.03
316	I	I	-4.91	-4.91
317	N	N	-1.98	-1.98
318	Y	Y	-4.18	-4.18
319	L	L	-0.31	-0.31
320	K	K	3.3	3.3
321	A	A	-0.08	-0.08
322	G	G	-1.38	-1.38
323	K	K	0.05	0.05
324	L	L	-1.11	-1.11
325	D	D	-0.0	-0.0
326	D	D	-3.25	-3.25
327	V	V	-0.63	-0.63
328	L	L	-5.94	-5.94
329	T	T	-1.57	-1.57
330	I	I	-0.97	-0.97
331	K	K	3.49	3.49
332	G	G	-0.08	-0.08
333	E	E	-0.53	-0.53
334	C	C	-0.86	-0.86
335	V	V	-0.93	-0.93
336	H	H	0.12	0.12
337	Q	Q	-0.07	-0.07
338	G	G	0.34	0.34
339	R	R	6.45	6.45
340	T	T	1.4	1.4
341	T	T	-1.71	-1.71
342	C	C	-0.84	-0.84
343	V	V	-4.21	-4.21
344	M	M	1.9	1.9
345	D	D	-0.71	-0.71
346	V	V	-4.18	-4.18
347	D	D	0.72	0.72
348	I	I	-6.24	-6.24
349	T	T	-2.55	-2.55
350	N	N	-2.54	-2.54
351	Q	Q	1.94	1.94
352	E	E	-0.09	-0.09
353	G	G	-1.98	-1.98
354	R	R	2.47	2.47
355	N	N	2.38	2.38
356	V	V	-4.14	-4.14
357	C	C	-1.81	-1.81
358	K	K	1.5	1.5
359	A	A	-2.66	-2.66
360	T	T	-1.73	-1.73
361	F	F	-3.69	-3.69
362	T	T	-1.64	-1.64
363	M	M	-2.89	-2.89
364	F	F	-4.87	-4.87
365	V	V	-2.99	-2.99
366	T	T	-1.97	-1.97
367	G	G	-1.75	-1.75
368	Q	Q	22.77	22.77
369	R	R	8.07	8.07
370	F	F	0.05	0.05
371	H	H	1.52	1.52
372	F	F	-2.87	-2.87
373	D	D	-1.51	-1.51
374	A	A	-2.02	-2.02
375	I	I	-1.09	-1.09
376	S	S	0.26	0.26
377	A	A	-1.88	-1.88
378	F	F	-2.3	-2.3
379	E	E	3.3	3.3
380	N	N	-0.27	-0.27
381	Y	Y	-2.87	-2.87
382	E	E	0.34	0.34
383	I	I	-1.19	-1.19
384	E	E	-0.79	-0.79
385	K	K	-0.88	-0.88
386	M	M	1.77	1.77
387	R	R	7.23	7.23
388	D	D	0.2	0.2
389	G	G	-2.87	-2.87
390	H	H	0.74	0.74
391	V	V	-3.85	-3.85
392	V	V	-3.29	-3.29
393	V	V	-5.21	-5.21
394	T	T	-1.97	-1.97
395	T	T	-1.95	-1.95
396	K	K	-3.35	-3.35
397	V	V	-4.89	-4.89
398	V	V	-0.65	-0.65
399	N	N	2.73	2.73
400	S	S	0.57	0.57
401	S	S	-0.31	-0.31
402	L	L	-4.29	-4.29
403	N	N	-2.37	-2.37
404	Y	Y	4.86	4.86
405	Y	Y	3.45	3.45
406	G	G	-2.34	-2.34
407	N	N	-2.79	-2.79
408	A	A	-3.08	-3.08
409	H	H	-4.85	-4.85
410	G	G	-0.7	-0.7
411	G	G	-0.07	-0.07
412	Y	Y	-2.36	-2.36
413	L	L	-5.0	-5.0
414	F	F	-5.71	-5.71
415	T	T	-2.0	-2.0
416	L	L	-4.91	-4.91
417	C	C	-0.75	-0.75
418	D	D	0.39	0.39
419	Q	Q	0.33	0.33
420	I	I	-0.89	-0.89
421	S	S	-1.51	-1.51
422	G	G	-0.74	-0.74
423	L	L	-2.83	-2.83
424	V	V	-4.2	-4.2
425	V	V	-1.79	-1.79
426	I	I	-2.07	-2.07
427	S	S	-2.33	-2.33
428	L	L	-2.85	-2.85
429	G	G	-3.08	-3.08
430	L	L	-2.66	-2.66
431	D	D	-2.17	-2.17
432	G	G	-0.74	-0.74
433	V	V	15.56	15.56
434	T	T	-1.32	-1.32
435	L	L	-2.39	-2.39
436	Q	Q	-0.05	-0.05
437	S	S	-1.97	-1.97
438	S	S	-0.13	-0.13
439	I	I	-4.87	-4.87
440	N	N	-1.56	-1.56
441	Y	Y	-3.74	-3.74
442	L	L	-1.56	-1.56
443	K	K	1.87	1.87
444	A	A	0.01	0.01
445	G	G	-1.42	-1.42
446	K	K	-0.06	-0.06
447	L	L	-0.9	-0.9
448	D	D	0.48	0.48
449	D	D	-3.15	-3.15
450	V	V	-0.17	-0.17
451	L	L	-5.87	-5.87
452	T	T	-2.05	-2.05
453	I	I	-0.06	-0.06
454	K	K	-1.2	-1.2
455	G	G	0.05	0.05
456	E	E	0.64	0.64
457	C	C	-1.05	-1.05
458	V	V	-1.93	-1.93
459	H	H	0.68	0.68
460	Q	Q	0.02	0.02
461	G	G	0.75	0.75
462	R	R	19.94	19.94
463	T	T	-0.33	-0.33
464	T	T	-1.7	-1.7
465	C	C	-1.15	-1.15
466	V	V	-4.57	-4.57
467	M	M	1.9	1.9
468	D	D	1.57	1.57
469	V	V	-3.75	-3.75
470	D	D	1.1	1.1
471	I	I	-5.81	-5.81
472	T	T	-2.85	-2.85
473	N	N	-3.44	-3.44
474	Q	Q	1.84	1.84
475	E	E	-0.73	-0.73
476	G	G	-2.09	-2.09
477	R	R	0.69	0.69
478	N	N	-1.6	-1.6
479	V	V	-4.03	-4.03
480	C	C	-0.94	-0.94
481	K	K	6.44	6.44
482	A	A	-2.6	-2.6
483	T	T	-1.53	-1.53
484	F	F	-2.55	-2.55
485	T	T	-2.3	-2.3
486	M	M	-2.95	-2.95
487	F	F	-2.11	-2.11
488	V	V	-2.98	-2.98
489	T	T	-1.64	-1.64
490	G	G	-1.91	-1.91
491	Q	Q	6.0	6.0
492	R	R	-0.25	-0.25
493	S	S	2.81	2.81
494	S	S	7.5	7.5
495	N	N	3.11	3.11
496	A	A	1.48	1.48
497	M	M	1.18	1.18
498	K	K	4.0	4.0
499	D	D	1.46	1.46
500	F	F	-0.11	-0.11
501	H	H	-0.2	-0.2
502	F	F	2.46	2.46
503	D	D	-2.45	-2.45
504	A	A	-4.36	-4.36
505	I	I	4.23	4.23
506	S	S	1.2	1.2
507	A	A	-0.22	-0.22
508	F	F	4.72	4.72
509	E	E	1.77	1.77
510	N	N	-0.48	-0.48
511	Y	Y	-1.03	-1.03
512	E	E	-0.8	-0.8
513	I	I	-0.79	-0.79
514	E	E	-1.24	-1.24
515	K	K	-0.91	-0.91
516	M	M	1.31	1.31
517	R	R	7.5	7.5
518	D	D	0.64	0.64
519	G	G	-2.48	-2.48
520	H	H	1.26	1.26
521	V	V	-3.95	-3.95
522	V	V	-3.24	-3.24
523	V	V	-4.77	-4.77
524	T	T	-2.3	-2.3
525	T	T	-2.36	-2.36
526	K	K	-1.97	-1.97
527	V	V	-4.88	-4.88
528	V	V	-0.0	-0.0
529	N	N	0.57	0.57
530	S	S	1.17	1.17
531	S	S	0.23	0.23
532	L	L	-4.02	-4.02
533	N	N	-1.31	-1.31
534	Y	Y	0.45	0.45
535	Y	Y	1.01	1.01
536	G	G	-2.57	-2.57
537	N	N	-2.37	-2.37
538	A	A	-1.99	-1.99
539	H	H	3.07	3.07
540	G	G	-0.14	-0.14
541	G	G	1.58	1.58
542	Y	Y	-1.39	-1.39
543	L	L	-5.21	-5.21
544	F	F	-5.6	-5.6
545	T	T	0.35	0.35
546	L	L	-4.55	-4.55
547	C	C	-0.96	-0.96
548	D	D	-0.16	-0.16
549	Q	Q	13.23	13.23
550	I	I	-1.09	-1.09
551	S	S	-0.99	-0.99
552	G	G	-0.3	-0.3
553	L	L	-3.12	-3.12
554	V	V	-4.19	-4.19
555	V	V	-0.71	-0.71
556	I	I	-0.95	-0.95
557	S	S	-2.7	-2.7
558	L	L	-3.76	-3.76
559	G	G	-0.37	-0.37
560	L	L	-3.0	-3.0
561	D	D	3.41	3.41
562	G	G	-0.67	-0.67
563	V	V	0.25	0.25
564	T	T	-0.79	-0.79
565	L	L	-2.76	-2.76
566	Q	Q	0.63	0.63
567	S	S	-2.33	-2.33
568	S	S	-0.26	-0.26
569	I	I	-5.0	-5.0
570	N	N	-1.64	-1.64
571	Y	Y	-2.43	-2.43
572	L	L	-1.71	-1.71
573	K	K	5.26	5.26
574	A	A	0.28	0.28
575	G	G	-0.98	-0.98
576	K	K	0.45	0.45
577	L	L	-0.65	-0.65
578	D	D	-1.24	-1.24
579	D	D	-3.04	-3.04
580	V	V	-0.45	-0.45
581	L	L	-5.8	-5.8
582	T	T	-2.01	-2.01
583	I	I	-1.43	-1.43
584	K	K	-1.41	-1.41
585	G	G	-0.06	-0.06
586	E	E	1.45	1.45
587	C	C	-0.99	-0.99
588	V	V	-0.85	-0.85
589	H	H	0.04	0.04
590	Q	Q	-0.06	-0.06
591	G	G	1.3	1.3
592	R	R	4.18	4.18
593	T	T	1.9	1.9
594	T	T	-1.34	-1.34
595	C	C	-1.27	-1.27
596	V	V	-4.94	-4.94
597	M	M	2.5	2.5
598	D	D	-0.57	-0.57
599	V	V	-3.27	-3.27
600	D	D	0.1	0.1
601	I	I	-5.8	-5.8
602	T	T	-3.07	-3.07
603	N	N	-3.76	-3.76
604	Q	Q	2.1	2.1
605	E	E	7.04	7.04
606	G	G	-1.87	-1.87
607	R	R	1.55	1.55
608	N	N	-0.6	-0.6
609	V	V	-3.88	-3.88
610	C	C	-1.25	-1.25
611	K	K	0.95	0.95
612	A	A	-2.49	-2.49
613	T	T	-1.75	-1.75
614	F	F	-3.9	-3.9
615	T	T	-2.33	-2.33
616	M	M	4.79	4.79
617	F	F	-1.71	-1.71
618	V	V	-3.57	-3.57
619	T	T	-1.94	-1.94
620	G	G	-1.67	-1.67
621	Q	Q	7.61	7.61
622	X	X	10.17	10.17
623	A	A	2.12	2.12
624	M	M	9.97	9.97
625	K	K	7.37	7.37
626	D	D	1.28	1.28
627	F	F	-0.81	-0.81
628	H	H	-0.66	-0.66
629	F	F	0.07	0.07
630	D	D	-3.35	-3.35
631	A	A	-3.29	-3.29
632	I	I	2.55	2.55
633	S	S	0.57	0.57
634	A	A	-0.63	-0.63
635	F	F	-0.53	-0.53
636	E	E	1.76	1.76
637	N	N	-0.74	-0.74
638	Y	Y	-0.04	-0.04
639	E	E	2.12	2.12
640	I	I	-1.37	-1.37
641	E	E	3.43	3.43
642	K	K	4.61	4.61
643	M	M	1.38	1.38
644	R	R	10.05	10.05
645	D	D	1.28	1.28
646	G	G	-2.84	-2.84
647	H	H	17.22	17.22
648	V	V	-3.71	-3.71
649	V	V	-3.89	-3.89
650	V	V	-4.72	-4.72
651	T	T	-0.65	-0.65
652	T	T	-1.92	-1.92
653	K	K	-2.52	-2.52
654	V	V	-4.02	-4.02
655	V	V	-0.03	-0.03
656	N	N	5.5	5.5
657	S	S	1.23	1.23
658	S	S	-0.21	-0.21
659	L	L	-4.51	-4.51
660	N	N	-3.27	-3.27
661	Y	Y	-0.07	-0.07
662	Y	Y	0.89	0.89
663	G	G	-2.42	-2.42
664	N	N	-1.4	-1.4
665	A	A	-2.46	-2.46
666	H	H	-0.01	-0.01
667	G	G	-0.02	-0.02
668	G	G	1.62	1.62
669	Y	Y	-1.61	-1.61
670	L	L	-5.19	-5.19
671	F	F	-5.68	-5.68
672	T	T	-1.06	-1.06
673	L	L	-5.12	-5.12
674	C	C	0.62	0.62
675	D	D	0.6	0.6
676	Q	Q	-1.01	-1.01
677	I	I	-0.3	-0.3
678	S	S	-1.3	-1.3
679	G	G	-0.1	-0.1
680	L	L	-1.72	-1.72
681	V	V	-3.92	-3.92
682	V	V	-0.65	-0.65
683	I	I	-1.44	-1.44
684	S	S	-2.35	-2.35
685	L	L	-3.79	-3.79
686	G	G	-2.92	-2.92
687	L	L	-2.97	-2.97
688	D	D	-1.4	-1.4
689	G	G	-0.81	-0.81
690	V	V	0.59	0.59
691	T	T	-0.66	-0.66
692	L	L	-1.85	-1.85
693	Q	Q	0.28	0.28
694	S	S	-2.5	-2.5
695	S	S	-0.45	-0.45
696	I	I	-4.96	-4.96
697	N	N	-1.5	-1.5
698	Y	Y	-2.36	-2.36
699	L	L	-2.16	-2.16
700	K	K	6.3	6.3
701	A	A	0.32	0.32
702	G	G	-0.91	-0.91
703	K	K	-0.92	-0.92
704	L	L	0.03	0.03
705	D	D	0.59	0.59
706	D	D	-3.58	-3.58
707	V	V	-0.61	-0.61
708	L	L	-6.03	-6.03
709	T	T	-1.58	-1.58
710	I	I	-2.87	-2.87
711	K	K	13.75	13.75
712	G	G	0.27	0.27
713	E	E	1.27	1.27
714	C	C	-0.93	-0.93
715	V	V	-2.86	-2.86
716	H	H	0.47	0.47
717	Q	Q	-0.48	-0.48
718	G	G	1.07	1.07
719	R	R	3.66	3.66
720	T	T	2.24	2.24
721	T	T	-1.25	-1.25
722	C	C	-1.55	-1.55
723	V	V	-5.16	-5.16
724	M	M	1.58	1.58
725	D	D	1.66	1.66
726	V	V	-3.46	-3.46
727	D	D	1.95	1.95
728	I	I	-5.72	-5.72
729	T	T	-2.93	-2.93
730	N	N	-3.35	-3.35
731	Q	Q	1.75	1.75
732	E	E	0.37	0.37
733	G	G	-2.07	-2.07
734	R	R	1.56	1.56
735	N	N	-1.52	-1.52
736	V	V	-3.81	-3.81
737	C	C	5.61	5.61
738	K	K	5.12	5.12
739	A	A	-2.87	-2.87
740	T	T	-1.71	-1.71
741	F	F	-1.08	-1.08
742	T	T	-2.33	-2.33
743	M	M	-1.9	-1.9
744	F	F	-1.89	-1.89
745	V	V	-3.45	-3.45
746	T	T	-1.89	-1.89
747	G	G	-1.86	-1.86
748	Q	Q	2.13	2.13
749	R	R	9.09	9.09
750	S	S	2.25	2.25
751	X	X	7.42	7.42
752	M	M	6.5	6.5
753	K	K	10.07	10.07
754	D	D	0.49	0.49
755	F	F	-1.78	-1.78
756	H	H	1.04	1.04
757	F	F	0.01	0.01
758	D	D	-3.37	-3.37
759	A	A	-3.53	-3.53
760	I	I	17.3	17.3
761	S	S	0.74	0.74
762	A	A	-0.46	-0.46
763	F	F	0.64	0.64
764	E	E	0.45	0.45
765	N	N	-0.78	-0.78
766	Y	Y	4.23	4.23
767	E	E	0.2	0.2
768	I	I	-0.89	-0.89
769	E	E	-0.34	-0.34
770	K	K	2.1	2.1
771	M	M	1.59	1.59
772	R	R	8.16	8.16
773	D	D	3.66	3.66
774	G	G	-3.17	-3.17
775	H	H	0.43	0.43
776	V	V	-3.64	-3.64
777	V	V	-1.57	-1.57
778	V	V	-4.77	-4.77
779	T	T	-1.69	-1.69
780	T	T	-2.0	-2.0
781	K	K	4.49	4.49
782	V	V	-4.05	-4.05
783	V	V	-0.21	-0.21
784	N	N	3.37	3.37
785	S	S	0.54	0.54
786	S	S	0.1	0.1
787	L	L	-3.5	-3.5
788	N	N	-3.17	-3.17
789	Y	Y	0.29	0.29
790	Y	Y	-0.05	-0.05
791	G	G	-2.49	-2.49
792	N	N	-2.0	-2.0
793	A	A	-2.53	-2.53
794	H	H	0.36	0.36
795	G	G	-0.11	-0.11
796	G	G	1.53	1.53
797	Y	Y	-1.75	-1.75
798	L	L	-5.16	-5.16
799	F	F	-5.8	-5.8
800	T	T	-0.75	-0.75
801	L	L	-4.7	-4.7
802	C	C	-0.32	-0.32
803	D	D	0.6	0.6
804	Q	Q	-1.13	-1.13
805	I	I	-0.24	-0.24
806	S	S	-1.37	-1.37
807	G	G	0.02	0.02
808	L	L	2.83	2.83
809	V	V	-4.21	-4.21
810	V	V	-0.75	-0.75
811	I	I	-1.81	-1.81
812	S	S	-2.96	-2.96
813	L	L	-3.59	-3.59
814	G	G	-0.31	-0.31
815	L	L	-2.64	-2.64
816	D	D	2.36	2.36
817	G	G	-0.97	-0.97
818	V	V	0.48	0.48
819	T	T	-0.8	-0.8
820	L	L	13.21	13.21
821	Q	Q	1.62	1.62
822	S	S	-2.39	-2.39
823	S	S	-0.4	-0.4
824	I	I	-5.05	-5.05
825	N	N	-1.39	-1.39
826	Y	Y	-2.16	-2.16
827	L	L	-1.88	-1.88
828	K	K	2.0	2.0
829	A	A	0.34	0.34
830	G	G	-0.9	-0.9
831	K	K	-0.99	-0.99
832	L	L	0.49	0.49
833	D	D	0.21	0.21
834	D	D	-2.93	-2.93
835	V	V	-0.32	-0.32
836	L	L	-5.6	-5.6
837	T	T	-2.03	-2.03
838	I	I	0.16	0.16
839	K	K	0.97	0.97
840	G	G	-0.12	-0.12
841	E	E	-1.14	-1.14
842	C	C	-0.93	-0.93
843	V	V	-2.63	-2.63
844	H	H	0.57	0.57
845	Q	Q	-0.34	-0.34
846	G	G	1.04	1.04
847	R	R	9.21	9.21
848	T	T	1.79	1.79
849	T	T	-0.96	-0.96
850	C	C	-1.44	-1.44
851	V	V	-5.32	-5.32
852	M	M	1.86	1.86
853	D	D	2.07	2.07
854	V	V	-3.39	-3.39
855	D	D	2.26	2.26
856	I	I	-5.33	-5.33
857	T	T	-2.87	-2.87
858	N	N	-3.6	-3.6
859	Q	Q	2.42	2.42
860	E	E	0.26	0.26
861	G	G	-1.98	-1.98
862	R	R	1.89	1.89
863	N	N	-1.1	-1.1
864	V	V	-3.58	-3.58
865	C	C	-1.01	-1.01
866	K	K	7.32	7.32
867	A	A	-2.43	-2.43
868	T	T	-2.17	-2.17
869	F	F	-2.37	-2.37
870	T	T	-2.46	-2.46
871	M	M	-1.88	-1.88
872	F	F	-2.02	-2.02
873	V	V	-3.53	-3.53
874	T	T	-1.91	-1.91
875	G	G	-1.4	-1.4
876	Q	Q	8.52	8.52
877	R	R	12.89	12.89
878	X	X	8.04	8.04
879	A	A	2.47	2.47
880	M	M	2.2	2.2
881	K	K	4.41	4.41
882	D	D	2.27	2.27
883	F	F	-2.84	-2.84
884	H	H	0.78	0.78
885	F	F	0.47	0.47
886	D	D	-3.73	-3.73
887	A	A	-3.64	-3.64
888	I	I	3.36	3.36
889	S	S	1.38	1.38
890	A	A	-0.67	-0.67
891	F	F	8.92	8.92
892	E	E	1.09	1.09
893	N	N	-0.67	-0.67
894	Y	Y	-1.06	-1.06
895	E	E	-0.61	-0.61
896	I	I	-0.79	-0.79
897	E	E	-1.11	-1.11
898	K	K	0.13	0.13
899	M	M	1.67	1.67
900	R	R	8.49	8.49
901	D	D	-0.16	-0.16
902	G	G	-3.42	-3.42
903	H	H	-0.65	-0.65
904	V	V	-3.8	-3.8
905	V	V	-3.43	-3.43
906	V	V	-5.09	-5.09
907	T	T	-2.08	-2.08
908	T	T	-2.44	-2.44
909	K	K	4.3	4.3
910	V	V	-4.84	-4.84
911	V	V	-0.21	-0.21
912	N	N	0.57	0.57
913	S	S	0.75	0.75
914	S	S	0.17	0.17
915	L	L	-4.06	-4.06
916	N	N	-1.46	-1.46
917	Y	Y	-0.21	-0.21
918	Y	Y	0.04	0.04
919	G	G	-2.45	-2.45
920	N	N	-1.95	-1.95
921	A	A	-2.06	-2.06
922	H	H	2.93	2.93
923	G	G	-0.16	-0.16
924	G	G	1.47	1.47
925	Y	Y	-1.37	-1.37
926	L	L	-5.19	-5.19
927	F	F	-5.6	-5.6
928	T	T	-0.16	-0.16
929	L	L	-4.42	-4.42
930	C	C	-1.49	-1.49
931	D	D	-0.36	-0.36
932	Q	Q	11.63	11.63
933	I	I	-1.16	-1.16
934	S	S	-1.13	-1.13
935	G	G	-0.26	-0.26
936	L	L	-3.25	-3.25
937	V	V	-4.04	-4.04
938	V	V	-0.07	-0.07
939	I	I	-0.81	-0.81
940	S	S	-2.81	-2.81
941	L	L	-3.6	-3.6
942	G	G	-0.74	-0.74
943	L	L	-2.72	-2.72
944	D	D	0.64	0.64
945	G	G	-0.67	-0.67
946	V	V	0.27	0.27
947	T	T	-0.89	-0.89
948	L	L	-2.52	-2.52
949	Q	Q	0.61	0.61
950	S	S	-2.07	-2.07
951	S	S	0.09	0.09
952	I	I	-5.02	-5.02
953	N	N	-1.6	-1.6
954	Y	Y	-2.38	-2.38
955	L	L	-1.57	-1.57
956	K	K	2.69	2.69
957	A	A	0.47	0.47
958	G	G	-1.0	-1.0
959	K	K	3.53	3.53
960	L	L	-0.56	-0.56
961	D	D	0.02	0.02
962	D	D	-3.47	-3.47
963	V	V	-0.52	-0.52
964	L	L	-5.83	-5.83
965	T	T	-1.55	-1.55
966	I	I	-0.91	-0.91
967	K	K	0.45	0.45
968	G	G	0.07	0.07
969	E	E	1.11	1.11
970	C	C	-0.94	-0.94
971	V	V	-1.06	-1.06
972	H	H	0.14	0.14
973	Q	Q	-0.13	-0.13
974	G	G	1.37	1.37
975	R	R	3.43	3.43
976	T	T	4.42	4.42
977	T	T	-0.93	-0.93
978	C	C	-1.29	-1.29
979	V	V	-4.77	-4.77
980	M	M	2.37	2.37
981	D	D	-0.56	-0.56
982	V	V	-3.8	-3.8
983	D	D	-0.1	-0.1
984	I	I	-5.85	-5.85
985	T	T	-2.46	-2.46
986	N	N	-3.16	-3.16
987	Q	Q	2.18	2.18
988	E	E	-0.42	-0.42
989	G	G	-1.98	-1.98
990	R	R	1.19	1.19
991	N	N	1.82	1.82
992	V	V	-3.84	-3.84
993	C	C	-1.72	-1.72
994	K	K	1.03	1.03
995	A	A	-2.33	-2.33
996	T	T	-1.28	-1.28
997	F	F	-3.87	-3.87
998	T	T	-1.15	-1.15
999	M	M	4.0	4.0
1000	F	F	-1.09	-1.09
1001	V	V	-3.21	-3.21
1002	T	T	-1.87	-1.87
1003	G	G	-1.72	-1.72
1004	Q	Q	5.89	5.89
1005	X	X	12.65	12.65

Analysis of pair 4zrbH_4zrbC

Figure 1: Two structures (Fold1 & Fold2)

Figure 2: Two structures aligned

Figure 3: Deep-MSA contact map panel

Figure 4: Best clusters contact map panel

Figure 5: All clusters contact-map mosaic (small multiples).

Per-cluster contact maps

Figure 6: Aligned per-residue ΔΔG (seq alignment overlay).

Figure 7: Phylogenetic tree with per-cluster heatmap.

Cluster metrics table

Aligned per-residue ΔΔG