Analysis of pair 4xwsD_4y0mJ

4xwsD vs 4y0mJ

Figure 1: Two structures (Fold1 & Fold2)

Figure 2: Two structures aligned

Figure 3: Fold1 vs best AF2

Figure 4: Fold2 vs best AF2

Figure 5: Fold1 vs best AF3

Figure 6: Fold2 vs best AF3

Missing: Fold1 vs best ESM2
Missing: Fold2 vs best ESM2

Figure 7: Fold1 vs best ESM3

Figure 8: Fold2 vs best ESM3

[missing] 4xwsD vs. 4y0mJ (unaligned) — interactive
[missing] 4xwsD vs. 4y0mJ (aligned) — interactive

Figure 9: Deep-MSA contact map panel

Figure 10: Best clusters contact map panel

Figure 11: All clusters contact-map mosaic (small multiples).

Per-cluster contact maps

Figure 12: Aligned per-residue ΔΔG (seq alignment overlay).

Figure 13: Phylogenetic tree with per-cluster heatmap.

Cluster metrics table

clusternneffAF2_TM1AF2_TM2AF3_TM1AF3_TM2RE-MSAT-COMRE-MSAT1RE-MSAT2ESM_SEQIDSESM_TM1_LISTESM_TM2_LIST
Deep--0.950.950.960.94-0.510.19---
000--0.840.80.850.780.080.070.07006; 004; 006; 004; 005; 005; 002; 002; 001; 0010.83; 0.83; 0.83; 0.83; 0.82; 0.82; 0.81; 0.81; 0.80; 0.800.88; 0.86; 0.88; 0.86; 0.82; 0.82; 0.82; 0.82; 0.79; 0.79
001--0.620.560.730.650.050.070.05003; 003; 006; 006; 004; 004; 007; 007; 001; 0010.85; 0.85; 0.83; 0.83; 0.82; 0.82; 0.81; 0.81; 0.77; 0.770.91; 0.91; 0.87; 0.87; 0.86; 0.86; 0.84; 0.84; 0.79; 0.79
002--0.910.820.920.840.10.080.08009; 009; 005; 005; 006; 006; 001; 001; 002; 0020.84; 0.84; 0.84; 0.84; 0.81; 0.81; 0.80; 0.80; 0.79; 0.790.90; 0.90; 0.88; 0.88; 0.86; 0.86; 0.81; 0.81; 0.80; 0.80
003--0.930.860.930.860.090.070.08005; 005; 007; 004; 007; 004; 001; 001; 008; 0080.84; 0.84; 0.82; 0.81; 0.81; 0.81; 0.80; 0.80; 0.79; 0.790.88; 0.88; 0.88; 0.87; 0.88; 0.87; 0.86; 0.86; 0.80; 0.80
004--0.910.840.920.850.10.080.08001; 004; 004; 001; 008; 008; 006; 006; 002; 0020.84; 0.84; 0.84; 0.84; 0.81; 0.81; 0.78; 0.78; 0.73; 0.730.86; 0.90; 0.90; 0.86; 0.85; 0.85; 0.84; 0.84; 0.78; 0.78
005--0.810.750.810.730.080.080.07004; 004; 001; 001; 006; 006; 002; 002; 003; 0030.85; 0.85; 0.83; 0.83; 0.79; 0.79; 0.78; 0.78; 0.77; 0.770.89; 0.89; 0.85; 0.85; 0.88; 0.88; 0.80; 0.80; 0.77; 0.77
006--0.880.810.880.80.10.080.08005; 005; 007; 007; 001; 001; 003; 003; 006; 0020.84; 0.84; 0.81; 0.81; 0.80; 0.80; 0.78; 0.78; 0.74; 0.740.89; 0.89; 0.85; 0.85; 0.80; 0.80; 0.82; 0.82; 0.75; 0.77
007--0.940.950.950.94-0.360.12001; 001; 007; 007; 008; 008; 006; 006; 005; 0050.87; 0.87; 0.84; 0.84; 0.84; 0.84; 0.80; 0.80; 0.76; 0.760.88; 0.88; 0.92; 0.92; 0.92; 0.92; 0.83; 0.83; 0.82; 0.82
008--0.870.830.860.830.080.060.06005; 005; 001; 001; 004; 004; 002; 002; 007; 0080.85; 0.85; 0.81; 0.81; 0.75; 0.75; 0.74; 0.74; 0.72; 0.720.92; 0.92; 0.82; 0.82; 0.77; 0.77; 0.75; 0.75; 0.73; 0.77
009--0.850.790.840.780.10.080.08006; 006; 007; 007; 001; 001; 008; 004; 008; 0040.84; 0.84; 0.82; 0.82; 0.81; 0.81; 0.79; 0.79; 0.79; 0.780.89; 0.89; 0.84; 0.84; 0.79; 0.79; 0.84; 0.81; 0.84; 0.81
010--0.820.750.840.770.080.060.08009; 009; 010; 010; 007; 007; 001; 001; 002; 0020.85; 0.85; 0.84; 0.83; 0.80; 0.80; 0.79; 0.79; 0.75; 0.750.87; 0.87; 0.82; 0.82; 0.87; 0.87; 0.81; 0.81; 0.77; 0.77
011--0.890.790.90.80.090.060.08006; 006; 008; 008; 001; 001; 005; 005; 007; 0070.86; 0.86; 0.85; 0.85; 0.82; 0.82; 0.81; 0.81; 0.76; 0.760.91; 0.91; 0.89; 0.89; 0.82; 0.82; 0.88; 0.88; 0.80; 0.80
012--0.810.770.810.750.080.10.08008; 008; 004; 004; 001; 007; 003; 001; 007; 0030.84; 0.84; 0.81; 0.81; 0.77; 0.77; 0.77; 0.77; 0.77; 0.770.88; 0.88; 0.83; 0.83; 0.79; 0.85; 0.78; 0.79; 0.85; 0.78
013--0.90.840.890.840.080.060.07008; 008; 001; 001; 005; 005; 006; 002; 002; 0060.83; 0.83; 0.82; 0.82; 0.78; 0.78; 0.74; 0.74; 0.74; 0.740.89; 0.89; 0.85; 0.85; 0.83; 0.83; 0.79; 0.77; 0.77; 0.79
014--0.760.70.740.670.070.060.08008; 008; 007; 007; 005; 006; 006; 005; 004; 0040.84; 0.84; 0.83; 0.83; 0.81; 0.81; 0.81; 0.81; 0.79; 0.790.88; 0.88; 0.88; 0.88; 0.84; 0.85; 0.85; 0.84; 0.83; 0.83
015--0.530.50.630.60.080.070.07005; 005; 007; 007; 006; 006; 001; 004; 001; 0040.83; 0.83; 0.81; 0.81; 0.78; 0.78; 0.72; 0.72; 0.72; 0.720.85; 0.85; 0.85; 0.85; 0.81; 0.81; 0.71; 0.74; 0.71; 0.74
016--0.870.80.860.770.070.060.06009; 009; 006; 006; 001; 007; 001; 007; 005; 0050.85; 0.85; 0.84; 0.84; 0.82; 0.82; 0.82; 0.82; 0.80; 0.800.89; 0.89; 0.89; 0.89; 0.83; 0.85; 0.83; 0.85; 0.84; 0.84
017--0.90.840.90.840.070.060.07007; 007; 008; 008; 006; 009; 006; 009; 001; 0010.85; 0.85; 0.84; 0.84; 0.83; 0.83; 0.83; 0.83; 0.81; 0.810.89; 0.89; 0.90; 0.90; 0.89; 0.87; 0.89; 0.87; 0.83; 0.83
018--0.860.770.820.760.080.070.08008; 008; 005; 005; 006; 006; 007; 007; 001; 0010.84; 0.84; 0.83; 0.83; 0.81; 0.81; 0.80; 0.80; 0.79; 0.790.89; 0.89; 0.88; 0.88; 0.87; 0.87; 0.87; 0.87; 0.79; 0.78
019--0.890.80.870.780.080.060.08007; 006; 006; 007; 005; 005; 001; 001; 002; 0020.85; 0.85; 0.85; 0.85; 0.84; 0.84; 0.80; 0.80; 0.73; 0.730.88; 0.89; 0.89; 0.88; 0.88; 0.88; 0.78; 0.78; 0.75; 0.75