Analysis of pair 4rmbB_4rmbA
4rmbB vs 4rmbA
[missing] Two structures (Fold1 & Fold2)
[missing] Two structures aligned
Missing: Fold1 vs best AF2
Missing: Fold2 vs best AF2
Missing: Fold1 vs best AF3
Missing: Fold2 vs best AF3
Missing: Fold1 vs best ESM2
Missing: Fold2 vs best ESM2
Missing: Fold1 vs best ESM3
Missing: Fold2 vs best ESM3
[missing] 4rmbB vs. 4rmbA (unaligned) — interactive
[missing] 4rmbB vs. 4rmbA (aligned) — interactive
[missing] Deep-MSA contact map panel / Best clusters contact map panel
[missing] All clusters contact-map mosaic (small multiples).
[missing] Aligned per-residue ΔΔG (seq alignment overlay).
[missing] Phylogenetic tree with per-cluster heatmap.
Cluster metrics table
| cluster | n | neff | AF2_TM1 | AF2_TM2 | AF3_TM1 | AF3_TM2 | RE-MSAT-COM | RE-MSAT1 | RE-MSAT2 | ESM_SEQIDS | ESM_TM1_LIST | ESM_TM2_LIST |
|---|
| Deep | - | - | 0.84 | 0.84 | 0.85 | 0.85 | 0.09 | 0.08 | 0.09 | 4rmbB; 4rmbB; 4rmbA; 4rmbA | 0.77; 0.77; 0.73; 0.72 | 0.77; 0.77; 0.73; 0.72 |
Aligned per-residue ΔΔG
| aln_pos | aa1 | aa2 | E1 | E2 | dEdiff |
|---|
| 1 | Q | Q | 5.23 | 5.23 | 0.0 |
| 2 | T | T | 12.64 | 12.64 | 0.0 |
| 3 | E | E | 18.43 | 18.43 | 0.0 |
| 4 | T | T | -2.43 | -2.43 | 0.0 |
| 5 | Y | Y | -3.75 | -3.75 | 0.0 |
| 6 | I | I | -0.6 | -0.6 | 0.0 |
| 7 | T | T | -2.82 | -2.82 | 0.0 |
| 8 | Q | Q | -2.38 | -2.38 | 0.0 |
| 9 | I | I | -4.31 | -4.31 | 0.0 |
| 10 | N | N | -1.22 | -1.22 | 0.0 |
| 11 | P | P | 0.74 | 0.74 | 0.0 |
| 12 | E | E | 0.33 | 0.33 | 0.0 |
| 13 | G | G | 0.47 | 0.47 | 0.0 |
| 14 | K | K | -1.42 | -1.42 | 0.0 |
| 15 | E | E | 1.12 | 1.12 | 0.0 |
| 16 | M | M | 0.16 | 0.16 | 0.0 |
| 17 | Y | Y | 2.39 | 2.39 | 0.0 |
| 18 | F | F | 0.85 | 0.85 | 0.0 |
| 19 | A | A | -0.35 | -0.35 | 0.0 |
| 20 | S | S | 1.96 | 1.96 | 0.0 |
| 21 | G | G | -0.69 | -0.69 | 0.0 |
| 22 | L | L | -2.07 | -2.07 | 0.0 |
| 23 | G | G | -0.44 | -0.44 | 0.0 |
| 24 | N | N | -2.24 | -2.24 | 0.0 |
| 25 | L | L | -4.14 | -4.14 | 0.0 |
| 26 | Y | Y | -2.41 | -2.41 | 0.0 |
| 27 | T | T | 2.66 | 2.66 | 0.0 |
| 28 | I | I | -2.27 | -2.27 | 0.0 |
| 29 | I | I | -4.42 | -4.42 | 0.0 |
| 30 | G | G | -3.04 | -3.04 | 0.0 |
| 31 | S | S | 3.16 | 3.16 | 0.0 |
| 32 | D | D | 4.92 | 4.92 | 0.0 |
| 33 | G | G | 4.18 | 4.18 | 0.0 |
| 34 | S | S | 7.62 | 7.62 | 0.0 |
| 35 | P | P | 3.17 | 3.17 | 0.0 |
| 36 | V | V | -3.57 | -3.57 | 0.0 |
| 37 | N | N | -2.8 | -2.8 | 0.0 |
| 38 | L | L | -4.56 | -4.56 | 0.0 |
| 39 | L | L | 0.19 | 0.19 | 0.0 |
| 40 | N | N | 1.54 | 1.54 | 0.0 |
| 41 | A | A | -2.76 | -2.76 | 0.0 |
| 42 | E | E | 1.86 | 1.86 | 0.0 |
| 43 | V | V | -3.45 | -3.45 | 0.0 |
| 44 | K | K | 6.93 | 6.93 | 0.0 |
| 45 | I | I | -7.38 | -7.38 | 0.0 |
| 46 | L | L | -1.35 | -1.35 | 0.0 |
| 47 | K | K | 3.23 | 3.23 | 0.0 |
| 48 | T | T | -0.76 | -0.76 | 0.0 |
| 49 | N | N | -0.6 | -0.6 | 0.0 |
| 50 | S | S | 1.17 | 1.17 | 0.0 |
| 51 | K | K | 4.58 | 4.58 | 0.0 |
| 52 | N | N | 1.13 | 1.13 | 0.0 |
| 53 | L | L | 1.31 | 1.31 | 0.0 |
| 54 | T | T | 36.57 | 36.57 | 0.0 |
| 55 | N | N | 8.3 | 8.3 | 0.0 |
| 56 | Y | Y | -0.47 | -0.47 | 0.0 |
| 57 | D | D | 3.16 | 3.16 | 0.0 |
| 58 | S | S | 13.34 | 13.34 | 0.0 |
| 59 | P | P | 5.0 | 5.0 | 0.0 |
| 60 | E | E | 1.38 | 1.38 | 0.0 |
| 61 | F | F | -2.67 | -2.67 | 0.0 |
| 62 | E | E | -0.68 | -0.68 | 0.0 |
| 63 | D | D | -1.3 | -1.3 | 0.0 |
| 64 | V | V | -3.08 | -3.08 | 0.0 |
| 65 | T | T | -1.55 | -1.55 | 0.0 |
| 66 | S | S | 2.13 | 2.13 | 0.0 |
| 67 | Q | Q | 2.52 | 2.52 | 0.0 |
| 68 | Y | Y | -1.65 | -1.65 | 0.0 |
| 69 | S | S | 2.69 | 2.69 | 0.0 |
| 70 | Y | Y | -1.26 | -1.26 | 0.0 |
| 71 | T | T | 0.85 | 0.85 | 0.0 |
| 72 | N | N | -1.77 | -1.77 | 0.0 |
| 73 | D | D | 1.64 | 1.64 | 0.0 |
| 74 | G | G | -2.72 | -2.72 | 0.0 |
| 75 | S | S | -1.81 | -1.81 | 0.0 |
| 76 | K | K | 2.45 | 2.45 | 0.0 |
| 77 | I | I | -4.04 | -4.04 | 0.0 |
| 78 | T | T | -1.54 | -1.54 | 0.0 |
| 79 | I | I | -5.49 | -5.49 | 0.0 |
| 80 | D | D | -3.37 | -3.37 | 0.0 |
| 81 | W | W | -5.56 | -5.56 | 0.0 |
| 82 | K | K | -1.51 | -1.51 | 0.0 |
| 83 | T | T | 0.37 | 0.37 | 0.0 |
| 84 | N | N | 0.59 | 0.59 | 0.0 |
| 85 | S | S | -1.04 | -1.04 | 0.0 |
| 86 | I | I | -2.92 | -2.92 | 0.0 |
| 87 | S | S | -0.1 | -0.1 | 0.0 |
| 88 | S | S | 0.2 | 0.2 | 0.0 |
| 89 | T | T | 0.53 | 0.53 | 0.0 |
| 90 | T | T | 3.21 | 3.21 | 0.0 |
| 91 | S | S | -1.4 | -1.4 | 0.0 |
| 92 | Y | Y | -5.1 | -5.1 | 0.0 |
| 93 | V | V | -4.88 | -4.88 | 0.0 |
| 94 | V | V | -5.22 | -5.22 | 0.0 |
| 95 | L | L | 1.69 | 1.69 | 0.0 |
| 96 | V | V | -4.04 | -4.04 | 0.0 |
| 97 | K | K | 10.76 | 10.76 | 0.0 |
| 98 | I | I | -1.75 | -1.75 | 0.0 |
| 99 | P | P | -3.07 | -3.07 | 0.0 |
| 100 | K | K | -0.15 | -0.15 | 0.0 |
| 101 | Q | Q | -2.15 | -2.15 | 0.0 |
| 102 | S | S | 1.94 | 1.94 | 0.0 |
| 103 | G | G | -1.56 | -1.56 | 0.0 |
| 104 | V | V | -0.94 | -0.94 | 0.0 |
| 105 | L | L | 4.47 | 4.47 | 0.0 |
| 106 | Y | Y | -3.11 | -3.11 | 0.0 |
| 107 | S | S | -2.62 | -2.62 | 0.0 |
| 108 | T | T | -2.09 | -2.09 | 0.0 |
| 109 | V | V | -0.27 | -0.27 | 0.0 |
| 110 | S | S | -0.51 | -0.51 | 0.0 |
| 111 | D | D | -1.68 | -1.68 | 0.0 |
| 112 | I | I | 1.28 | 1.28 | 0.0 |
| 113 | N | N | -0.62 | -0.62 | 0.0 |
| 114 | Q | Q | -1.85 | -1.85 | 0.0 |
| 115 | T | T | -2.11 | -2.11 | 0.0 |
| 116 | Y | Y | -0.2 | -0.2 | 0.0 |
| 117 | G | G | -2.51 | -2.51 | 0.0 |
| 118 | S | S | -1.68 | -1.68 | 0.0 |
| 119 | K | K | 1.81 | 1.81 | 0.0 |
| 120 | Y | Y | -0.65 | -0.65 | 0.0 |
| 121 | S | S | -1.41 | -1.41 | 0.0 |
| 122 | Y | Y | -1.45 | -1.45 | 0.0 |
| 123 | G | G | 0.3 | 0.3 | 0.0 |
| 124 | H | H | 2.19 | 2.19 | 0.0 |
| 125 | T | T | 9.69 | 9.69 | 0.0 |
| 126 | N | N | 2.65 | 2.65 | 0.0 |
| 127 | I | I | 0.65 | 0.65 | 0.0 |
| 128 | S | S | 2.44 | 2.44 | 0.0 |
| 129 | G | G | 0.48 | 0.48 | 0.0 |
| 130 | D | D | 1.1 | 1.1 | 0.0 |
| 131 | S | S | 0.12 | 0.12 | 0.0 |
| 132 | D | D | 0.63 | 0.63 | 0.0 |
| 133 | A | A | -0.78 | -0.78 | 0.0 |
| 134 | N | N | -2.86 | -2.86 | 0.0 |
| 135 | A | A | -1.87 | -1.87 | 0.0 |
| 136 | E | E | 3.49 | 3.49 | 0.0 |
| 137 | I | I | -3.19 | -3.19 | 0.0 |
| 138 | K | K | -3.14 | -3.14 | 0.0 |
| 139 | L | L | 2.14 | 2.14 | 0.0 |
| 140 | L | L | 14.59 | 14.59 | 0.0 |
| 141 | S | S | 1.83 | 1.83 | 0.0 |
| 142 | R | R | 5.82 | 5.82 | 0.0 |
| 143 | Q | Q | 23.08 | 23.08 | 0.0 |
| 144 | T | T | 0.19 | 0.19 | 0.0 |
| 145 | E | E | 7.72 | 7.72 | 0.0 |
| 146 | T | T | -2.59 | -2.59 | 0.0 |
| 147 | Y | Y | -2.97 | -2.97 | 0.0 |
| 148 | I | I | -3.2 | -3.2 | 0.0 |
| 149 | T | T | -2.92 | -2.92 | 0.0 |
| 150 | Q | Q | -2.49 | -2.49 | 0.0 |
| 151 | I | I | -4.13 | -4.13 | 0.0 |
| 152 | N | N | -4.6 | -4.6 | 0.0 |
| 153 | P | P | 4.83 | 4.83 | 0.0 |
| 154 | E | E | -2.68 | -2.68 | 0.0 |
| 155 | G | G | -0.74 | -0.74 | 0.0 |
| 156 | K | K | 1.46 | 1.46 | 0.0 |
| 157 | E | E | 0.39 | 0.39 | 0.0 |
| 158 | M | M | -1.25 | -1.25 | 0.0 |
| 159 | Y | Y | 1.33 | 1.33 | 0.0 |
| 160 | F | F | -0.12 | -0.12 | 0.0 |
| 161 | A | A | -0.06 | -0.06 | 0.0 |
| 162 | S | S | 0.99 | 0.99 | 0.0 |
| 163 | G | G | -0.31 | -0.31 | 0.0 |
| 164 | L | L | -2.54 | -2.54 | 0.0 |
| 165 | G | G | -0.49 | -0.49 | 0.0 |
| 166 | N | N | -1.9 | -1.9 | 0.0 |
| 167 | L | L | 7.12 | 7.12 | 0.0 |
| 168 | Y | Y | -1.03 | -1.03 | 0.0 |
| 169 | T | T | 2.34 | 2.34 | 0.0 |
| 170 | I | I | 0.95 | 0.95 | 0.0 |
| 171 | I | I | -4.27 | -4.27 | 0.0 |
| 172 | G | G | -3.0 | -3.0 | 0.0 |
| 173 | S | S | 0.52 | 0.52 | 0.0 |
| 174 | D | D | 4.6 | 4.6 | 0.0 |
| 175 | G | G | 19.88 | 19.88 | 0.0 |
| 176 | S | S | 0.97 | 0.97 | 0.0 |
| 177 | P | P | -1.89 | -1.89 | 0.0 |
| 178 | V | V | -2.39 | -2.39 | 0.0 |
| 179 | N | N | -2.81 | -2.81 | 0.0 |
| 180 | L | L | -5.4 | -5.4 | 0.0 |
| 181 | L | L | 0.04 | 0.04 | 0.0 |
| 182 | N | N | 1.66 | 1.66 | 0.0 |
| 183 | A | A | -2.74 | -2.74 | 0.0 |
| 184 | E | E | 0.61 | 0.61 | 0.0 |
| 185 | V | V | -3.22 | -3.22 | 0.0 |
| 186 | K | K | -1.85 | -1.85 | 0.0 |
| 187 | I | I | -7.03 | -7.03 | 0.0 |
| 188 | L | L | -3.74 | -3.74 | 0.0 |
| 189 | K | K | -0.53 | -0.53 | 0.0 |
| 190 | T | T | 0.43 | 0.43 | 0.0 |
| 191 | N | N | 0.45 | 0.45 | 0.0 |
| 192 | S | S | 4.5 | 4.5 | 0.0 |
| 193 | K | K | 4.23 | 4.23 | 0.0 |
| 194 | N | N | 6.99 | 6.99 | 0.0 |
| 195 | L | L | 4.89 | 4.89 | 0.0 |
| 196 | T | T | 0.94 | 0.94 | 0.0 |
| 197 | D | D | 3.82 | 3.82 | 0.0 |
| 198 | S | S | 2.59 | 2.59 | 0.0 |
| 199 | M | M | 7.51 | 7.51 | 0.0 |
| 200 | D | D | 23.78 | 23.78 | 0.0 |
| 201 | Q | Q | 7.77 | 7.77 | 0.0 |
| 202 | N | N | 3.79 | 3.79 | 0.0 |
| 203 | Y | Y | -2.65 | -2.65 | 0.0 |
| 204 | D | D | 3.58 | 3.58 | 0.0 |
| 205 | S | S | 3.06 | 3.06 | 0.0 |
| 206 | P | P | 0.2 | 0.2 | 0.0 |
| 207 | E | E | 3.11 | 3.11 | 0.0 |
| 208 | F | F | -0.75 | -0.75 | 0.0 |
| 209 | E | E | 1.28 | 1.28 | 0.0 |
| 210 | D | D | -0.43 | -0.43 | 0.0 |
| 211 | V | V | -2.39 | -2.39 | 0.0 |
| 212 | T | T | -0.9 | -0.9 | 0.0 |
| 213 | S | S | 1.89 | 1.89 | 0.0 |
| 214 | Q | Q | 2.8 | 2.8 | 0.0 |
| 215 | Y | Y | -1.24 | -1.24 | 0.0 |
| 216 | S | S | 3.45 | 3.45 | 0.0 |
| 217 | Y | Y | -1.11 | -1.11 | 0.0 |
| 218 | T | T | 2.2 | 2.2 | 0.0 |
| 219 | N | N | -0.79 | -0.79 | 0.0 |
| 220 | D | D | -1.84 | -1.84 | 0.0 |
| 221 | G | G | -2.89 | -2.89 | 0.0 |
| 222 | S | S | -1.75 | -1.75 | 0.0 |
| 223 | K | K | 9.03 | 9.03 | 0.0 |
| 224 | I | I | -3.98 | -3.98 | 0.0 |
| 225 | T | T | -1.59 | -1.59 | 0.0 |
| 226 | I | I | -5.43 | -5.43 | 0.0 |
| 227 | D | D | -2.86 | -2.86 | 0.0 |
| 228 | W | W | -5.77 | -5.77 | 0.0 |
| 229 | K | K | 2.25 | 2.25 | 0.0 |
| 230 | T | T | -0.0 | -0.0 | 0.0 |
| 231 | N | N | -1.31 | -1.31 | 0.0 |
| 232 | S | S | -1.07 | -1.07 | 0.0 |
| 233 | I | I | 0.16 | 0.16 | 0.0 |
| 234 | S | S | -0.57 | -0.57 | 0.0 |
| 235 | S | S | -0.17 | -0.17 | 0.0 |
| 236 | T | T | 1.47 | 1.47 | 0.0 |
| 237 | T | T | -1.05 | -1.05 | 0.0 |
| 238 | S | S | 0.53 | 0.53 | 0.0 |
| 239 | Y | Y | -5.47 | -5.47 | 0.0 |
| 240 | V | V | -4.18 | -4.18 | 0.0 |
| 241 | V | V | -5.43 | -5.43 | 0.0 |
| 242 | L | L | -3.76 | -3.76 | 0.0 |
| 243 | V | V | -4.2 | -4.2 | 0.0 |
| 244 | K | K | 1.4 | 1.4 | 0.0 |
| 245 | I | I | -0.73 | -0.73 | 0.0 |
| 246 | P | P | -1.37 | -1.37 | 0.0 |
| 247 | K | K | 17.14 | 17.14 | 0.0 |
| 248 | Q | Q | -1.54 | -1.54 | 0.0 |
| 249 | S | S | 0.2 | 0.2 | 0.0 |
| 250 | G | G | -1.71 | -1.71 | 0.0 |
| 251 | V | V | -1.5 | -1.5 | 0.0 |
| 252 | L | L | -4.76 | -4.76 | 0.0 |
| 253 | Y | Y | -2.3 | -2.3 | 0.0 |
| 254 | S | S | -1.68 | -1.68 | 0.0 |
| 255 | T | T | -2.57 | -2.57 | 0.0 |
| 256 | V | V | -1.17 | -1.17 | 0.0 |
| 257 | S | S | -0.1 | -0.1 | 0.0 |
| 258 | D | D | -1.68 | -1.68 | 0.0 |
| 259 | I | I | 1.5 | 1.5 | 0.0 |
| 260 | N | N | -1.37 | -1.37 | 0.0 |
| 261 | Q | Q | 1.95 | 1.95 | 0.0 |
| 262 | T | T | -0.88 | -0.88 | 0.0 |
| 263 | Y | Y | -1.91 | -1.91 | 0.0 |
| 264 | G | G | -3.08 | -3.08 | 0.0 |
| 265 | S | S | -0.66 | -0.66 | 0.0 |
| 266 | K | K | -2.71 | -2.71 | 0.0 |
| 267 | Y | Y | -3.5 | -3.5 | 0.0 |
| 268 | S | S | -1.75 | -1.75 | 0.0 |
| 269 | Y | Y | -1.38 | -1.38 | 0.0 |
| 270 | G | G | -1.81 | -1.81 | 0.0 |
| 271 | H | H | -0.56 | -0.56 | 0.0 |
| 272 | T | T | -0.32 | -0.32 | 0.0 |
| 273 | N | N | -1.61 | -1.61 | 0.0 |
| 274 | I | I | 1.55 | 1.55 | 0.0 |
| 275 | S | S | 1.61 | 1.61 | 0.0 |
| 276 | G | G | -1.84 | -1.84 | 0.0 |
| 277 | D | D | 0.25 | 0.25 | 0.0 |
| 278 | S | S | 1.03 | 1.03 | 0.0 |
| 279 | D | D | 2.66 | 2.66 | 0.0 |
| 280 | A | A | 1.29 | 1.29 | 0.0 |
| 281 | N | N | -1.58 | -1.58 | 0.0 |
| 282 | A | A | -0.52 | -0.52 | 0.0 |
| 283 | E | E | -0.34 | -0.34 | 0.0 |
| 284 | I | I | -0.2 | -0.2 | 0.0 |
| 285 | K | K | 1.97 | 1.97 | 0.0 |
| 286 | L | L | -4.98 | -4.98 | 0.0 |
| 287 | L | L | -2.71 | -2.71 | 0.0 |
| 288 | S | S | -0.44 | -0.44 | 0.0 |
| 289 | L | L | -1.42 | -1.42 | 0.0 |
| 290 | E | E | -1.43 | -1.43 | 0.0 |
| 291 | H | H | 6.45 | 6.45 | 0.0 |
| 292 | H | H | 4.22 | 4.22 | 0.0 |
| 293 | H | H | 6.62 | 6.62 | 0.0 |
| 294 | H | H | 4.98 | 4.98 | 0.0 |
| 295 | H | H | 7.48 | 7.48 | 0.0 |
| 296 | H | H | 4.23 | 4.23 | 0.0 |